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选择性引产与期待管理在宫颈条件不佳的初产妇中的比较。

Elective induction compared with expectant management in nulliparous women with an unfavorable cervix.

机构信息

From the Department of Obstetrics and Gynecology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois.

出版信息

Obstet Gynecol. 2011 Mar;117(3):583-587. doi: 10.1097/AOG.0b013e31820caf12.

Abstract

OBJECTIVES

To compare outcomes of labor between nulliparas with an unfavorable cervix who underwent either elective labor induction or expectant management beyond 39 weeks of gestation.

METHODS

We conducted a retrospective cohort study of nulliparous women with a singleton gestation who had an unfavorable cervix (modified Bishop score less than 5) and delivered between 2006 and 2008. One hundred two nulliparous women who underwent elective induction of labor between 39 and 40 5/7 weeks of gestation were compared with 102 nulliparous women who were expectantly managed beyond 39 weeks of gestation.

RESULTS

The primary outcome, cesarean delivery, was not statistically different between women who were expectantly managed and those who underwent elective labor induction (34.3% compared with 43.1%, respectively, P=.16). Aside from the more frequent occurrence of meconium in the expectantly managed group (36.3% compared with 7.0%, P<.001), there were no significant differences in other maternal (eg, chorioamnionitis, operative vaginal delivery, third-degree and fourth-degree lacerations, postpartum hemorrhage) or neonatal (arterial cord pH less than 7.0, Apgar score less than 7 at 5 minutes, neonatal intensive care unit admission) outcomes. Women who underwent an elective induction of labor did have longer duration of labor and delivery between admission and delivery (median 16.5 compared with 12.7 hours, P<.001).

CONCLUSIONS

For nulliparous women with an unfavorable cervix, elective labor induction increased utilization of labor and delivery resources but did not result in other significant differences in most clinical outcomes.

摘要

目的

比较宫颈条件不佳的初产妇行选择性引产与超过 39 孕周期待管理的分娩结局。

方法

我们对 2006 年至 2008 年间行剖宫产分娩的宫颈条件不佳(改良 Bishop 评分<5 分)且单胎妊娠的初产妇进行了回顾性队列研究。将 102 例行择期 39~40 5/7 孕周引产的初产妇与 102 例超过 39 孕周期待管理的初产妇进行比较。

结果

主要结局(剖宫产)在期待管理组与择期引产组之间无统计学差异(分别为 34.3%和 43.1%,P=.16)。除期待管理组胎粪污染更为常见(36.3%比 7.0%,P<.001)外,两组间其他产妇结局(如绒毛膜羊膜炎、经阴道分娩、Ⅲ度和Ⅳ度会阴裂伤、产后出血)或新生儿结局(脐动脉血 pH 值<7.0、5 分钟 Apgar 评分<7、新生儿重症监护病房入住)均无显著差异。行择期引产的产妇从入院到分娩的产程和总产程时间均更长(中位数分别为 16.5 小时比 12.7 小时,P<.001)。

结论

对于宫颈条件不佳的初产妇,选择性引产增加了产程和分娩资源的利用,但在大多数临床结局方面并未导致其他显著差异。

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