Koroglu Mehmet, Yakupogullari Yusuf, Otlu Baris, Ozturk Serhat, Ozden Mehmet, Ozer Ali, Sener Kemal, Durmaz Riza
Clinic Microbiology Resident, Malatya State Hospital, Clinic Microbiology Department, Malatya-Turkey.
New Microbiol. 2011 Jan;34(1):17-24. Epub 2011 Jan 15.
We characterized an outbreak of acute diarrheal disease caused by group A rotavirus that occurred during the Autumn of 2005 in Malatya City, Turkey. A total 9907 patients between 0 to 91 years old (mean age: 25.05�19.67) were included in the epidemic. The patients� data were prospectively collected and statistically analyzed. Microbiologic analyses were performed to determine the etiologic agent. Rapid onset diarrhea (98.36%), abdominal cramps (69%), fever (44.4%) and vomiting (69.6%) were the most common symptoms observed in patients. Rotavirus antigen was detected in 52.7% of the studied patients. RT-PCR analysis led to identification of Group A rotavirus as the causative agent of this epidemic. Simultaneous measurements of the drinking water samples yielded very low chlorine levels; as low as 0 to 0.05 mg/L. The outbreak investigation team indicated possible contamination of a large water depository from a water well, which supplies drinking water to two major districts of the city. Effective chlorination and blockage of the passage between the well and the water depository stopped the outbreak. This outbreak shows the high epidemic potency of rotavirus in large human populations, including all age groups, and underlines the importance of water safety in pipeline systems.
我们对2005年秋季在土耳其马拉蒂亚市发生的由A组轮状病毒引起的急性腹泻病暴发进行了特征描述。共有9907名年龄在0至91岁（平均年龄：25.05±19.67岁）的患者被纳入此次疫情。前瞻性收集患者数据并进行统计分析。进行微生物学分析以确定病原体。快速起病的腹泻（98.36%）、腹部绞痛（69%）、发热（44.4%）和呕吐（69.6%）是患者中观察到的最常见症状。在52.7%的研究患者中检测到轮状病毒抗原。逆转录聚合酶链反应（RT-PCR）分析确定A组轮状病毒是此次疫情的病原体。同时对饮用水样本的检测显示氯含量极低；低至0至0.05毫克/升。疫情调查小组指出，一口为该市两个主要城区供水的水井可能污染了一个大型储水池。有效的氯化处理以及阻断水井与储水池之间的通道阻止了疫情的蔓延。此次疫情表明轮状病毒在包括所有年龄组的大量人群中具有很高的流行潜力，并强调了管道系统中饮用水安全的重要性。
