Northwest Permanente, Portland, OR, USA.
Pediatr Infect Dis J. 2011 Aug;30(8):719-21. doi: 10.1097/INF.0b013e3182137e35.
Varicella vaccination of children has decreased varicella disease incidence, but introduced the occurrence of herpes zoster (HZ) from vaccine-type virus. We identified 14 vaccinated children with suspected HZ and confirmed varicella virus by polymerase chain reaction in 6 cases. Two cases were due to vaccine-type virus. Serum varicella IgM and IgG were not useful for diagnosis of HZ among vaccinated children.
儿童水痘疫苗接种降低了水痘疾病的发病率,但也导致了由疫苗株病毒引起的带状疱疹(HZ)的发生。我们通过聚合酶链反应在 6 例中鉴定出 14 例疑似 HZ 的接种儿童,其中 2 例为疫苗株病毒。水痘病毒 IgM 和 IgG 血清学检测对于诊断接种儿童的 HZ 并不实用。