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造血干细胞移植患者的运动:经验教训及一项可行性研究的结果

Exercise in patients receiving hematopoietic stem cell transplantation: lessons learned and results from a feasibility study.

作者信息

Hacker Eileen Danaher, Larson Janet L, Peace David

机构信息

Department of Biobehavioral Health Science, College of Nursing, University of Illinois, Chicago, USA.

出版信息

Oncol Nurs Forum. 2011 Mar;38(2):216-23. doi: 10.1188/11.ONF.216-223.

DOI:10.1188/11.ONF.216-223
PMID:21356659
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3721148/
Abstract

PURPOSE/OBJECTIVES: To test the feasibility and acceptability of a strength-training intervention in patients receiving hematopoietic stem cell transplantation (HSCT).

DESIGN

One-group prospective, repeated-measures design.

SETTING

Academic medical center in the midwestern United States.

SAMPLE

Convenience sample of 10 patients receiving HSCT.

METHODS

The strength-training intervention consisted of a comprehensive program of progressive resistance to strengthen the upper body, lower body, and abdominal muscles using elastic resistance bands. Instruction and low-intensity training began while the patients were hospitalized and progressed to a moderate level immediately following discharge from the hospital. Training continued for six weeks following hospital discharge.

MAIN RESEARCH VARIABLES

Acceptability of the strength-training intervention was evaluated via subjective assessment and by determining the patient's ability to perform the exercises. Feasibility was evaluated by determining the number of patients who were able to complete the prescribed strength intervention and whether the patients used elastic resistance bands.

FINDINGS

The strength-training intervention was refined from an unsupervised, home-based program to a combination supervised and unsupervised program with weekly clinic visits. Patients reported that the exercises were very acceptable, although some started out at a very low intensity.

CONCLUSIONS

This pilot study demonstrates the feasibility and acceptability of the strength-training intervention. The level of supervision required for the strength-training intervention was higher than expected.

IMPLICATIONS FOR NURSING

Strength training may be an effective intervention to alleviate problems with decreased physical activity, reduced muscle mass, and fatigue in HSCT recipients. Additional research is needed.

摘要

目的/目标:测试造血干细胞移植(HSCT)患者进行力量训练干预的可行性和可接受性。

设计

单组前瞻性重复测量设计。

地点

美国中西部的学术医疗中心。

样本

10例接受HSCT的患者的便利样本。

方法

力量训练干预包括一个综合计划,使用弹力带进行渐进性阻力训练,以增强上肢、下肢和腹部肌肉。指导和低强度训练在患者住院期间开始,并在出院后立即进展到中等强度。出院后训练持续六周。

主要研究变量

通过主观评估和确定患者进行锻炼能力来评估力量训练干预的可接受性。通过确定能够完成规定力量干预的患者数量以及患者是否使用弹力带来评估可行性。

结果

力量训练干预从一个无监督的家庭计划改进为一个有监督和无监督相结合的计划,每周进行门诊随访。患者报告说这些锻炼非常容易接受,尽管有些患者开始时强度非常低。

结论

这项初步研究证明了力量训练干预的可行性和可接受性。力量训练干预所需的监督水平高于预期。

对护理的启示

力量训练可能是缓解HSCT受者身体活动减少、肌肉量减少和疲劳问题的有效干预措施。需要进一步研究。

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本文引用的文献

1
American College of Sports Medicine position stand. Progression models in resistance training for healthy adults.美国运动医学学院立场声明。健康成年人抗阻训练的进阶模式。
Med Sci Sports Exerc. 2009 Mar;41(3):687-708. doi: 10.1249/MSS.0b013e3181915670.
2
The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of myelodysplastic syndromes: an evidence-based review.细胞毒性疗法联合造血干细胞移植在骨髓增生异常综合征治疗中的作用:一项循证综述
Biol Blood Marrow Transplant. 2009 Feb;15(2):137-72. doi: 10.1016/j.bbmt.2008.12.003.
3
The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute myelogenous leukemia in adults: an evidence-based review.细胞毒性疗法联合造血干细胞移植在成人急性髓性白血病治疗中的作用:一项循证综述
Biol Blood Marrow Transplant. 2008 Feb;14(2):137-80. doi: 10.1016/j.bbmt.2007.11.002.
4
The relationship between cancer-related fatigue and patient satisfaction with quality of life in cancer.癌症相关疲劳与癌症患者生活质量满意度之间的关系。
J Pain Symptom Manage. 2007 Jul;34(1):40-7. doi: 10.1016/j.jpainsymman.2006.10.012. Epub 2007 May 25.
5
Ecological momentary assessment of fatigue in patients receiving intensive cancer therapy.接受强化癌症治疗患者疲劳的生态瞬时评估
J Pain Symptom Manage. 2007 Mar;33(3):267-75. doi: 10.1016/j.jpainsymman.2006.08.007.
6
Effects of exercise on breast cancer patients and survivors: a systematic review and meta-analysis.运动对乳腺癌患者及幸存者的影响:一项系统综述与荟萃分析。
CMAJ. 2006 Jul 4;175(1):34-41. doi: 10.1503/cmaj.051073.
7
Fatigue and physical activity in patients undergoing hematopoietic stem cell transplant.接受造血干细胞移植患者的疲劳与体力活动
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8
Individualized exercise program for the treatment of severe fatigue in patients after allogeneic hematopoietic stem-cell transplant: a pilot study.个体化运动方案治疗异基因造血干细胞移植术后患者严重疲劳的初步研究
Bone Marrow Transplant. 2006 May;37(10):945-54. doi: 10.1038/sj.bmt.1705343.
9
The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute lymphoblastic leukemia in adults: an evidence-based review.细胞毒性疗法联合造血干细胞移植在成人急性淋巴细胞白血病治疗中的作用:一项循证综述
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10
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J Strength Cond Res. 2005 Aug;19(3):717-20. doi: 10.1519/R-15954.1.