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Risk assessment in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms.

作者信息

Cazzola Mario

出版信息

Haematologica. 2011 Mar;96(3):349-52. doi: 10.3324/haematol.2010.030023.

DOI:10.3324/haematol.2010.030023
PMID:21357714
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3046263/
Abstract
摘要

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Risk assessment in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms.骨髓增生异常综合征和骨髓增生异常/骨髓增殖性肿瘤的风险评估
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1
Prognostic relevance of anemia and transfusion dependency in myelodysplastic syndromes and primary myelofibrosis.骨髓增生异常综合征和原发性骨髓纤维化中贫血及输血依赖的预后相关性
Haematologica. 2011 Jan;96(1):8-10. doi: 10.3324/haematol.2010.035519.
2
Risk stratification based on both disease status and extra-hematologic comorbidities in patients with myelodysplastic syndrome.基于疾病状态和骨髓增生异常综合征患者的血液外合并症的风险分层。
Haematologica. 2011 Mar;96(3):441-9. doi: 10.3324/haematol.2010.033506. Epub 2010 Dec 6.
3
Cytogenetic risk stratification in chronic myelomonocytic leukemia.慢性粒单核细胞白血病的细胞遗传学危险分层。
Haematologica. 2011 Mar;96(3):375-83. doi: 10.3324/haematol.2010.030957. Epub 2010 Nov 25.
4
IDH1 and IDH2 mutations in myeloid neoplasms--novel paradigms and clinical implications.髓系肿瘤中的异柠檬酸脱氢酶1和2突变——新范例及临床意义
Haematologica. 2010 Oct;95(10):1623-7. doi: 10.3324/haematol.2010.030015.
5
Next-generation sequencing of the TET2 gene in 355 MDS and CMML patients reveals low-abundance mutant clones with early origins, but indicates no definite prognostic value.对 355 例 MDS 和 CMML 患者的 TET2 基因进行下一代测序显示，具有早期起源的低丰度突变克隆，但无明确的预后价值。
Blood. 2010 Nov 11;116(19):3923-32. doi: 10.1182/blood-2010-03-274704. Epub 2010 Aug 6.
6
Next-generation sequencing technology reveals a characteristic pattern of molecular mutations in 72.8% of chronic myelomonocytic leukemia by detecting frequent alterations in TET2, CBL, RAS, and RUNX1.下一代测序技术通过检测 TET2、CBL、RAS 和 RUNX1 等基因的频繁改变，揭示了 72.8%慢性髓单核细胞白血病的分子突变特征模式。
J Clin Oncol. 2010 Aug 20;28(24):3858-65. doi: 10.1200/JCO.2009.27.1361. Epub 2010 Jul 19.
7
Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes.骨髓增生异常综合征中组蛋白甲基转移酶基因 EZH2 的体细胞突变。
Nat Genet. 2010 Aug;42(8):665-7. doi: 10.1038/ng.620. Epub 2010 Jul 4.
8
Prognostic classification and risk assessment in myelodysplastic syndromes.骨髓增生异常综合征的预后分类和风险评估。
Hematol Oncol Clin North Am. 2010 Apr;24(2):459-68. doi: 10.1016/j.hoc.2010.02.005.
9
Gene expression-based classification as an independent predictor of clinical outcome in juvenile myelomonocytic leukemia.基于基因表达的分类作为青少年骨髓单核细胞白血病临床结局的独立预测因子。
J Clin Oncol. 2010 Apr 10;28(11):1919-27. doi: 10.1200/JCO.2009.24.4426. Epub 2010 Mar 15.
10
Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia.多梳蛋白相关基因ASXL1在骨髓增生异常综合征和急性髓系白血病中频繁发生突变。
Leukemia. 2010 May;24(5):1062-5. doi: 10.1038/leu.2010.20. Epub 2010 Feb 25.