Chandola Rakesh M, Tiwari Samit, Kowar Manoj K, Choudhary Vivek
Department of Radiotherapy, Pt. J.N.M. Medical College and Dr. B.R.A.M. Hospital, Raipur, Chhattisgarh, India.
J Cancer Res Ther. 2010 Oct-Dec;6(4):421-6. doi: 10.4103/0973-1482.77068.
The conventional treatment planning system (TPS) gives analytical calculations with ± 15 to 20% dose, which may lead to over exposure of critical organs or under dose of target. It is to obtain dose distribution parameters of nucletron high dose rate (HDR) microselectron v2 (mHDR-v2) 192 Ir brachytherapy source by experiment and by calculated study using Monte Carlo (MC) EGSnrc code, and to find the similarity between them, and with any past study. To validate data, another MC GEANT4 study done in this work on the same source is also presented. Different software of the computer e.g. paint, excel, etc are employed for preparation of figures and graphs. The measured study of the source was done using an in-air ionization chamber, water phantom, and measurement set-up, while the calculated study was done by modeling the set up of the measured study by using the MC EGSnrc and GEANT4. Mean and probability are used in calculation of average values, and calculation of the uncertainties in result and discussion. The measured and calculated values of dose rate constant, radial dose function, and 2D anisotropy function were found to be in agreement with each other as well as with published data. The results of this study can be used as input to TPS.
传统治疗计划系统（TPS）给出的分析计算剂量有±15%至20%的误差，这可能导致关键器官的剂量过度或靶区剂量不足。通过实验以及使用蒙特卡罗（MC）EGSnrc代码进行计算研究，来获取核通高剂量率（HDR）微型后装治疗机v2（mHDR-v2）192铱近距离治疗源的剂量分布参数，并找出它们之间以及与以往任何研究的相似性。为了验证数据，本文还展示了在同一源上进行的另一项MC GEANT4研究。使用计算机的不同软件，如画图软件、Excel等，来绘制图表。源的测量研究使用了空气中电离室、水模体和测量装置，而计算研究则是通过使用MC EGSnrc和GEANT4对测量研究的装置进行建模来完成的。在计算平均值以及结果和讨论中的不确定度时使用了均值和概率。剂量率常数、径向剂量函数和二维各向异性函数的测量值和计算值相互一致，并且与已发表的数据也一致。本研究的结果可作为TPS的输入。
