Neuroscience Intensive Care Unit, Departments of Neurosurgery and Neurology, Mount Sinai School of Medicine, One Gustave Levy Place, Box 1136, New York, NY 10029, USA.
Neurocrit Care. 2011 Jun;14(3):463-74. doi: 10.1007/s12028-011-9520-0.
Delirium is defined by a fluctuating level of attentiveness and has been associated with increased ICU mortality and poor cognitive outcomes in both general ICU and neurocritical care populations. Sedation use in the ICU can contribute to delirium. Limiting ICU sedation allows for the diagnosis of underlying acute neurological insults associated with delirium and leads to shorter mechanical ventilation time, shorter length of stay, and improved 1 year mortality rates. Identifying the underlying etiology of delirium is critical to developing treatment paradigms.
谵妄的定义是注意力波动，与 ICU 死亡率增加和普通 ICU 及神经重症监护人群认知结局不良有关。ICU 镇静的使用可能导致谵妄。限制 ICU 镇静可诊断与谵妄相关的潜在急性神经损伤，并导致机械通气时间更短、住院时间更短和 1 年死亡率改善。确定谵妄的潜在病因对于制定治疗方案至关重要。
