Nat Cell Biol. 2011 Mar;13(3):191-3. doi: 10.1038/ncb0311-191.
The adult human heart lacks sufficient regenerative capacity to recover after a myocardial infarction. Cell-based therapy has emerged as a potential treatment for the failing heart; however, a key issue for the success of future cell-based therapies is the ability to obtain patient-specific high-quality cardiomyocytes in a fast and efficient manner. Recent progress has been made towards this goal using reprogramming-based approaches.
成年人心肌梗死后缺乏足够的再生能力来恢复。基于细胞的疗法已成为治疗衰竭心脏的一种潜在方法；然而，未来基于细胞的治疗成功的一个关键问题是能够快速有效地获得患者特异性的高质量心肌细胞。最近在基于重编程的方法方面取得了进展。
