Division of Biology 156-29, California Institute of Technology, 1200 E. California Blvd, Pasadena, California 91125, USA.
Nat Rev Mol Cell Biol. 2011 Apr;12(4):265-73. doi: 10.1038/nrm3079. Epub 2011 Mar 2.
The emerging field of computational morphodynamics aims to understand the changes that occur in space and time during development by combining three technical strategies: live imaging to observe development as it happens; image processing and analysis to extract quantitative information; and computational modelling to express and test time-dependent hypotheses. The strength of the field comes from the iterative and combined use of these techniques, which has provided important insights into plant development.
计算形态动力学是一个新兴的领域,旨在通过结合三种技术策略来理解发育过程中随时间和空间发生的变化:活体成像以观察发育的进行;图像处理和分析以提取定量信息;以及计算建模以表达和测试时变假说。该领域的优势在于这些技术的迭代和综合使用,这为植物发育提供了重要的见解。