Key Laboratory for Microbial Resources, Ministry of Education, Yunnan Institute of Microbiology, Yunnan University, Kunming 650091, PR China.
Org Biomol Chem. 2011 Apr 21;9(8):2771-6. doi: 10.1039/c1ob05044c. Epub 2011 Mar 1.
Phenazinolins A-E (1-5), which possess a carbon skeleton unique to diphenazines (the azabicyclo[3.3.1]nonadienol moiety in 1-3 and the oxabicyclo[3.3.1]nonadienol moiety in 4 and 5), were isolated from tin mine tailings-derived Streptomyces diastaticus YIM DT26, with 1-3 exhibited appreciable cytotoxicity and antibiotic effects.
phenazinolins A-E (1-5),它们具有独特的二苯并嗪碳骨架(1-3 中的氮杂双环[3.3.1]壬醇部分和 4 和 5 中的氧杂双环[3.3.1]壬醇部分),从锡矿尾矿衍生的链霉菌 diastaticus YIM DT26 中分离出来,其中 1-3 表现出明显的细胞毒性和抗生素作用。