从锡矿尾矿衍生真菌裂褶菌YIM DT 10058中分离得到的两种新型二酮哌嗪。
Two new diketopiperazines from the tin mine tailings-derived fungus Schizophyllum commune YIM DT 10058.
作者信息
Chunyu Wei-Xun, Ding Zhang-Gui, Zhao Jiang-Yuan, Wang Yong-Xia, Han Xiu-Lin, Li Ming-Gang, Wen Meng-Liang
机构信息
a Key Laboratory for Conservation and Utilization of Bio-resource, and Key Laboratory for Microbial Resources of the Ministry of Education , Yunnan Institute of Microbiology, Yunnan University , Kunming , PR China.
b Key Laboratory of Medicinal Chemistry for Natural Resource of the Ministry of Education , Yunnan University , Kunming , PR China.
出版信息
Nat Prod Res. 2017 Jul;31(13):1566-1572. doi: 10.1080/14786419.2016.1274894. Epub 2017 Jan 11.
Two new diketopiperazines, named diphenylalazine C (1) and epicoccin U (2), together with six known compounds (3-8) were isolated from the EtOAc extract of the fermentation broth of the tin mine tailings-derived fungus Schizophyllum commune YIM DT 10058. Their structures were elucidated by detailed analysis of spectroscopic data and comparison with related known compounds. Compounds 1 and 2 exhibited weak antibacterial and cytotoxic activities.
从锡矿尾矿来源的真菌裂褶菌YIM DT 10058发酵液的乙酸乙酯提取物中分离得到两个新的二酮哌嗪，命名为二苯基丙氨酸嗪C（1）和表棒曲霉素U（2），以及六个已知化合物（3 - 8）。通过对光谱数据的详细分析并与相关已知化合物进行比较，阐明了它们的结构。化合物1和2表现出较弱的抗菌和细胞毒性活性。
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