糖皮质激素治疗、活动受限和便秘与营养风险相关。
Glucocorticoid treatment, immobility, and constipation are associated with nutritional risk.
机构信息
Division of Endocrinology, Diabetes and Clinical Nutrition, Bern University Hospital and University of Bern, Bern, Switzerland.
出版信息
Eur J Nutr. 2011 Dec;50(8):665-71. doi: 10.1007/s00394-011-0177-4. Epub 2011 Mar 3.
PURPOSE
The hypothesis of this clinical study was to determine whether glucocorticoid use and immobility were associated with in-hospital nutritional risk.
METHODS
One hundred and one patients consecutively admitted to the medical wards were enrolled. Current medical conditions, symptoms, medical history, eating and drinking habits, diagnosis, laboratory findings, medications, and anthropometrics were recorded. The Nutrition Risk Score 2002 (NRS-2002) was used as a screening instrument to identify nutritional risk.
RESULTS
The results confirmed that glucocorticoid use and immobility are independently associated with nutritional risk determined by the NRS-2002. Constipation could be determined as an additional cofactor independently associated with nutritional risk.
CONCLUSIONS
Glucocorticoid treatment, immobility, and constipation are associated with nutritional risk in a mixed hospitalized population. The presence of long-time glucocorticoid use, immobility, or constipation should alert the clinician to check for nutritional status, which is an important factor in mortality and morbidity.
目的
本临床研究的假设是确定糖皮质激素的使用和活动受限是否与住院期间的营养风险相关。
方法
连续纳入了 101 名入住内科病房的患者。记录了当前的医疗状况、症状、病史、饮食和饮水习惯、诊断、实验室检查结果、药物治疗以及人体测量学指标。使用营养风险评分 2002（NRS-2002）作为筛选工具来确定营养风险。
结果
结果证实，糖皮质激素的使用和活动受限与 NRS-2002 确定的营养风险独立相关。便秘可以确定为与营养风险独立相关的另一个伴随因素。
结论
糖皮质激素治疗、活动受限和便秘与混合住院人群的营养风险相关。长期使用糖皮质激素、活动受限或便秘的存在应引起临床医生注意，检查营养状况，这是死亡率和发病率的一个重要因素。
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