Center for Systems Biology, 185 Cambridge St, Boston, MA 02114, USA.
Circ Res. 2011 Mar 4;108(5):593-606. doi: 10.1161/CIRCRESAHA.110.232678.
Motivated by the promise to transform preclinical research and clinical care, cardiovascular molecular imaging has made advances toward targeting coronary atherosclerosis and heart failure. Here, we discuss recent progress in the field, highlight how molecular imaging may facilitate preventive patient care, and review specific challenges associated with coronary and heart failure imaging. Practical considerations stress the potential of fluorescence imaging for basic research and discuss hybrid protocols such as FMT-CT and PET-MRI.
受改变临床前研究和临床护理的承诺的激励，心血管分子成像在靶向冠状动脉粥样硬化和心力衰竭方面取得了进展。在这里，我们讨论了该领域的最新进展，强调了分子成像如何促进预防性患者护理，并回顾了与冠状动脉和心力衰竭成像相关的具体挑战。实际考虑因素强调了荧光成像在基础研究中的潜力，并讨论了 FMT-CT 和 PET-MRI 等混合方案。
