Tianjin Key Laboratory of Composite and Functional Materials, School of Materials Science and Engineering, Tianjin University, Tianjin 300072, People's Republic of China.
J Mater Sci Mater Med. 2011 Apr;22(4):1063-71. doi: 10.1007/s10856-011-4269-8. Epub 2011 Mar 4.
Inorganic-polymer nanocomposites are of significant interest for emerging materials due to their improved properties and unique combination of properties. Poly (methylmethacrylate) (PMMA)/montmorillonite (MMT) nanocomposites were prepared by in situ suspension polymerization with dodecylamine used as MMT-modifier. X-ray diffraction (XRD) and transmission electron microscopy (TEM) were used to characterize the structures of the nanocomposites. Cytotoxicity test, hemolysis test, acute systemic toxicity test, oral mucous membrane irritation test, guinea-pig maximization test and mouse bone-marrow micronucleus test were used to evaluate the biocompatibility of PMMA/MMT nanocomposites. The results indicated that an exfoliated nanocomposite was achieved, and the resulting nanocomposites exhibited excellent biocompatibility as denture base material and had potential application in dental materials.
无机-聚合物纳米复合材料因其改善的性能和独特的性能组合而受到新兴材料的关注。通过原位悬浮聚合制备了聚甲基丙烯酸甲酯（PMMA）/蒙脱土（MMT）纳米复合材料，并用十二胺作为 MMT 改性剂。采用 X 射线衍射（XRD）和透射电子显微镜（TEM）对纳米复合材料的结构进行了表征。采用细胞毒性试验、溶血试验、急性全身毒性试验、口腔黏膜刺激性试验、豚鼠最大试验和小鼠骨髓微核试验评价了 PMMA/MMT 纳米复合材料的生物相容性。结果表明，实现了剥离型纳米复合材料，所得纳米复合材料作为义齿基托材料表现出优异的生物相容性，在牙科材料中有潜在的应用。
