Glowacka-Sobotta Arleta, Ziental Daniel, Czarczynska-Goslinska Beata, Michalak Maciej, Wysocki Marcin, Güzel Emre, Sobotta Lukasz
Chair and Department of Orthodontics and Temporomandibular Disorders, Poznan University of Medical Sciences, Bukowska 70, 60-812 Poznan, Poland.
Chair and Department of Inorganic and Analytical Chemistry, Poznan University of Medical Sciences, Rokietnicka 3, 60-806 Poznan, Poland.
Nanomaterials (Basel). 2023 Jul 22;13(14):2130. doi: 10.3390/nano13142130.
In the XXI century, application of nanostructures in oral medicine has become common. In oral medicine, using nanostructures for the treatment of dental caries constitutes a great challenge. There are extensive studies on the implementation of nanomaterials to dental composites in order to improve their properties, e.g., their adhesive strength. Moreover, nanostructures are helpful in dental implant applications as well as in maxillofacial surgery for accelerated healing, promoting osseointegration, and others. Dental personal care products are an important part of oral medicine where nanomaterials are increasingly used, e.g., toothpaste for hypersensitivity. Nowadays, nanoparticles such as macrocycles are used in different formulations for early cancer diagnosis in the oral area. Cancer of the oral cavity-human squamous carcinoma-is the sixth leading cause of death. Detection in the early stage offers the best chance at total cure. Along with diagnosis, macrocycles are used for photodynamic mechanism-based treatments, which possess many advantages, such as protecting healthy tissues and producing good cosmetic results. Application of nanostructures in medicine carries potential risks, like long-term influence of toxicity on body, which need to be studied further. The introduction and development of nanotechnologies and nanomaterials are no longer part of a hypothetical future, but an increasingly important element of today's medicine.
在二十一世纪，纳米结构在口腔医学中的应用已变得十分普遍。在口腔医学中，利用纳米结构治疗龋齿是一项巨大的挑战。为了改善牙科复合材料的性能，如提高其粘结强度，人们对将纳米材料应用于牙科复合材料进行了广泛的研究。此外，纳米结构在牙种植体应用以及颌面外科手术中也有助于加速愈合、促进骨整合等。口腔护理产品是口腔医学的重要组成部分，纳米材料在其中的应用越来越广泛，例如用于治疗牙齿过敏的牙膏。如今，诸如大环化合物之类的纳米颗粒被用于不同配方中，以进行口腔区域早期癌症的诊断。口腔癌——人类鳞状细胞癌——是第六大致死原因。早期检测提供了完全治愈的最佳机会。除了诊断，大环化合物还用于基于光动力机制的治疗，这种治疗具有许多优点，如保护健康组织并产生良好的美容效果。纳米结构在医学中的应用存在潜在风险，如毒性对身体的长期影响，这需要进一步研究。纳米技术和纳米材料的引入与发展不再是未来的设想，而是当今医学中日益重要的元素。
