Department of Aviation, University of New South Wales, Sydney, NSW 2052, Australia.
Accid Anal Prev. 2011 May;43(3):690-7. doi: 10.1016/j.aap.2010.10.013. Epub 2010 Nov 26.
Time of day and the time since last sleep are acknowledged causes of fatigue, but comparatively little is known about how they interact. This study examines the relative effects of time of day and sleep deprivation on fatigue and performance. Two independent groups were exposed to 28 h of sleep deprivation beginning at 06:00 h for one group (n = 39) and at 00:00 h for the other (n = 22). By varying the start time for the two groups, but keeping constant the duration of sleep deprivation, the effects of variations in the time of day of testing could be examined. For the 06:00 h start group the longest period without sleep occurred close to the low point of the circadian rhythm. For the 00:00 h start group the circadian low point coincided with only two to six hours of sleep deprivation. Performance was evaluated two-hourly using eight computer-based tests and subjective fatigue ratings. The results showed a clear interaction effect. Both time of day and sleep deprivation affected performance but only in combination; neither had independent effects. These findings have implications for fatigue management.
昼夜时间和上次睡眠后的时间是公认的疲劳原因，但它们如何相互作用却知之甚少。本研究探讨了昼夜时间和睡眠剥夺对疲劳和表现的相对影响。两组独立的参与者从 06:00 开始被剥夺 28 小时的睡眠（一组 n=39），另一组从 00:00 开始（n=22）。通过改变两组的开始时间，但保持睡眠剥夺的持续时间不变，可以研究测试时间的昼夜变化的影响。对于 06:00 开始的小组，最长的无睡眠期发生在接近昼夜节律低点的时候。对于 00:00 开始的小组，昼夜节律的低点仅与两到六小时的睡眠剥夺相对应。使用八项基于计算机的测试和主观疲劳评分，每两小时评估一次表现。结果显示出明显的交互效应。昼夜时间和睡眠剥夺都影响表现，但只有在组合中才有影响；两者都没有独立的影响。这些发现对疲劳管理有影响。
