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利用基于粒度的粗糙集理论发现血液透析(HD)质量的知识。

Discovering knowledge of hemodialysis (HD) quality using granularity-based rough set theory.

机构信息

Department of Information Management, National Yunlin University of Science and Technology, 123 University Rd., Section 3, Douliou, Yunlin 640, Taiwan.

出版信息

Arch Gerontol Geriatr. 2012 Jan-Feb;54(1):232-7. doi: 10.1016/j.archger.2011.02.007. Epub 2011 Mar 5.

DOI:10.1016/j.archger.2011.02.007
PMID:21382641
Abstract

This study collected the real HD-data from area scale hospital database with 72 attributes and 18,113 records. The study proposes a novel procedure to assess the patient's HD-quality, including five facets: (1) Delete the unrelated attributes and missing values. (2) Employ expert granularity to cut decision-attributed Kt/V (where K is the dialyzer clearance coefficient of urea nitrogen, t is the time for dialysis and V is the urea nitrogen volume of distribution in the body). (3) Use information-gain to select features, to reduce the total number of attributes to 17. (4) Utilize multiple regression to test the degree of co-linearity and select features, the dimension of dataset is reduced to 8 attributes and 2737 records. (5) Finally, the rules of HD-quality and accuracy performance are generated by granular rough set theory. In performance comparison, the decision tree (DT-C4.5), the Naïve Bayes (NB) probabilistic model and Artificial Neural Networks-Multilayer Perceptrons (ANN-MLP) are employed to compare with the proposed procedure in accuracy. The results can assist doctors to reduce the time of diagnosis and to achieve dose of fitness-based dialysis for the patients.

摘要

本研究从区域规模医院数据库中收集了具有 72 个属性和 18113 条记录的真实 HD 数据。本研究提出了一种新的评估患者 HD 质量的程序,包括五个方面:(1)删除不相关的属性和缺失值。(2)采用专家粒度来切割决策属性 Kt/V(其中 K 是尿素氮的透析器清除系数,t 是透析时间,V 是体内尿素氮分布体积)。(3)使用信息增益选择特征,将属性总数减少到 17。(4)利用多元回归检验共线性程度并选择特征,数据集的维度减少到 8 个属性和 2737 条记录。(5)最后,利用粒状粗糙集理论生成 HD 质量和准确性性能的规则。在性能比较中,决策树(DT-C4.5)、朴素贝叶斯(NB)概率模型和人工神经网络-多层感知器(ANN-MLP)被用于与所提出的程序在准确性方面进行比较。这些结果可以帮助医生减少诊断时间,并为患者实现基于剂量的透析治疗。

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