Mansoor Aisha A, Salih Abdalla I, Al-Jaroudi Dania H
Obstetrics and Gynecology Department, Women's Specialized Hospital, King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia.
Saudi Med J. 2011 Mar;32(3):260-4.
To determine the prevalence of hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) in a group of infertile couples attending a tertiary care facility in Saudi Arabia.
A retrospective cross-sectional observational study was performed by reviewing medical records of 500 couples referred to the Reproductive Endocrine and Infertility Medicine Department of the Women's Specialized Hospital at King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia between January 2006 and December 2008. All patients were screened for HBV markers (hepatitis B surface antigen, hepatitis B surface antibody, hepatitis B core antibody, hepatitis Be antigen), anti-HCV, anti-HIV types I and II using enzyme linked immunoassay technique.
The overall prevalence of HBV in the population studied was 1.8% (n=17). For females HBV prevalence was 1.5% (n=7), and for males it was 2.1% (n=10). Overall HCV prevalence in this group was 0.5%. All females were negative for HCV, while males had a prevalence of 1.1% (n=5). All males and females were negative for HIV.
We found a high prevalence for HBV and HCV in a group of Saudi infertile population. The HIV prevalence was found to be 0%. Due to the risks of cross sectional and vertical transmission of these infections, and despite the low incidence of HIV infection and the cost implications, it is important to screen all Saudi infertile couples for these infections prior to embarking on fertility treatments.
确定在沙特阿拉伯一家三级医疗机构就诊的一组不孕夫妇中乙型肝炎病毒（HBV）、丙型肝炎病毒（HCV）和人类免疫缺陷病毒（HIV）的流行情况。
通过回顾2006年1月至2008年12月期间转诊至沙特阿拉伯利雅得法赫德国王医疗城妇女专科医院生殖内分泌与不孕医学科的500对夫妇的病历，进行了一项回顾性横断面观察研究。所有患者均采用酶联免疫吸附测定技术筛查HBV标志物（乙肝表面抗原、乙肝表面抗体、乙肝核心抗体、乙肝e抗原）、抗HCV、抗I型和II型HIV。
在所研究人群中，HBV的总体流行率为1.8%（n = 17）。女性HBV流行率为1.5%（n = 7），男性为2.1%（n = 10）。该组中HCV的总体流行率为0.5%。所有女性HCV检测均为阴性，而男性流行率为1.1%（n = 5）。所有男性和女性HIV检测均为阴性。
我们发现沙特一组不孕人群中HBV和HCV的流行率较高。HIV流行率为0%。由于这些感染存在交叉传播和垂直传播的风险，尽管HIV感染率较低且涉及成本问题，但在开始生育治疗之前，对所有沙特不孕夫妇进行这些感染的筛查非常重要。
