Tsujimoto T, Yamada N, Shimoda K, Hanada K, Takahashi S
Department of Psychiatry, Shiga University of Medical Science, Japan.
J Affect Disord. 1990 Mar;18(3):193-7. doi: 10.1016/0165-0327(90)90036-8.
In order to develop a sampling strategy and a method for analyzing the circadian body temperature pattern, we monitored estimates of the temperature in four ways using rectal, oral, axillary and deep body temperature from the skin surface every hour for 72 consecutive hours in 10 normal control subjects. Data obtained were analyzed with the least-squares method to estimate the circadian rhythm. Deep body temperature from the skin surface correlated better with rectal temperature than with either oral or axillary temperature in all subjects. The correlation coefficient between rectal and deep body temperature from the skin surface ranged between 0.66 and 0.89. The acrophases calculated from the deep body temperature from the skin surface every 2 h for 48 h were consistent with those based on the rectal temperature every 10 min for 72 h. We believe that monitoring of the deep body temperature from the skin surface, in this manner, at intervals of 2 h for a period of 2 days, is a promising method for investigating circadian body temperature rhythm, because it causes less discomfort than other measures and has greater statistical validity for data computation.
为了制定一种采样策略和一种分析昼夜体温模式的方法，我们对10名正常对照受试者连续72小时每小时通过直肠、口腔、腋窝和皮肤表面深部体温这四种方式监测体温估计值。对获得的数据采用最小二乘法进行分析以估计昼夜节律。在所有受试者中，皮肤表面深部体温与直肠体温的相关性优于与口腔或腋窝体温的相关性。直肠体温与皮肤表面深部体温之间的相关系数在0.66至0.89之间。每2小时从皮肤表面深部体温计算48小时的体温高峰相位与每10分钟从直肠体温计算72小时的体温高峰相位一致。我们认为，以这种方式每2小时监测一次皮肤表面深部体温，持续2天，是一种有前景的研究昼夜体温节律的方法，因为它比其他测量方法引起的不适更少，并且在数据计算方面具有更高的统计效度。
