Suppr超能文献

辅音三连音测试(CTT)表现与自闭症谱系障碍儿童日常工作记忆困难有关。

Impaired Consonant Trigrams Test (CTT) performance relates to everyday working memory difficulties in children with autism spectrum disorders.

机构信息

Children's Research Institute, Center for Neuroscience, Children's National Medical Center, Washington, DC, USA.

出版信息

Child Neuropsychol. 2011;17(4):391-9. doi: 10.1080/09297049.2010.547462.

Abstract

Individuals with Autism Spectrum Disorders (ASD) often struggle with complex tasks, such as those requiring divided attention (simultaneously completing two independent tasks) that also place high demands on working memory. Prior research shows that divided attention is impaired in adults and children with ASD and is related to ASD and comorbid attention deficit/hyperactivity disorder (ADHD) symptoms, but the impact on everyday functioning is unclear. Because ADHD symptoms are associated with poor divided attention and working memory performance in children with ASD, we also examined ADHD symptoms as moderators of divided attention performance. We examined performance on the Consonant Trigrams Test (CTT) between high-functioning 8- to 13-year-olds with ASD (n = 28) and typically developing controls (n = 18) matched on age and IQ. In the ASD group, we also correlated performance with ADHD symptoms and behavior ratings of everyday working memory. CTT performance in children with ASD was significantly worse than in matched controls. A significant correlation between CTT performance and everyday working memory was observed, but CTT performance was not related to comorbid ADHD symptoms in the ASD group. Divided attention with high working-memory demands is a relative weakness in children with high-functioning ASD; this weakness relates to everyday functioning, and it is independent from ADHD symptoms. That ADHD symptoms are not associated with divided attention performance is inconsistent with one prior investigation, which likely results from using different divided attention tasks in the two studies.

摘要

自闭症谱系障碍(ASD)个体通常难以完成复杂任务,例如需要注意力分配(同时完成两个独立的任务)且对工作记忆要求较高的任务。先前的研究表明,自闭症谱系障碍患者的注意力分配受损,且与自闭症谱系障碍和共患的注意缺陷多动障碍(ADHD)症状有关,但对日常功能的影响尚不清楚。由于 ADHD 症状与自闭症谱系障碍儿童的注意力分配和工作记忆表现差有关,因此我们还检查了 ADHD 症状是否为注意力分配表现的调节因素。我们在年龄和智商相匹配的高功能 8-13 岁自闭症谱系障碍儿童(n = 28)和典型发育对照组(n = 18)之间检查了辅音三连音测试(CTT)的表现。在自闭症谱系障碍组中,我们还将表现与 ADHD 症状和日常工作记忆的行为评定相关联。自闭症谱系障碍儿童的 CTT 表现明显差于匹配对照组。在自闭症谱系障碍组中,CTT 表现与日常工作记忆之间存在显著相关性,但与共患的 ADHD 症状无关。具有高工作记忆需求的注意力分配是高功能自闭症谱系障碍儿童的相对弱点;这种弱点与日常功能有关,且独立于 ADHD 症状。ADHD 症状与注意力分配表现无关与之前的一项研究不一致,这可能是由于两项研究使用了不同的注意力分配任务所致。

相似文献

5
Attention deficit hyperactivity disorder symptoms in adults with autism spectrum disorders.
Autism Res. 2013 Aug;6(4):225-36. doi: 10.1002/aur.1283. Epub 2013 Jun 20.
7
[Characteristics of executive function in children with attention deficit/hyperactivity disorder comorbid with high functioning autism].
Zhonghua Yi Xue Za Zhi. 2020 Aug 18;100(31):2446-2451. doi: 10.3760/cma.j.cn112137-20191216-02750.
10
[Executive function deficits in ADHD and Asperger syndrome].
Riv Psichiatr. 2013 Nov-Dec;48(6):441-7. doi: 10.1708/1379.15338.

引用本文的文献

1
Psychiatric Comorbidities in Children With ASD: Autism Centre Experience.
Front Psychiatry. 2021 Jun 9;12:673169. doi: 10.3389/fpsyt.2021.673169. eCollection 2021.
2
A meta-analysis of working memory in individuals with autism spectrum disorders.
PLoS One. 2019 Apr 30;14(4):e0216198. doi: 10.1371/journal.pone.0216198. eCollection 2019.
3
Psychiatric comorbidities in autism spectrum disorder: A comparative study between DSM-IV-TR and DSM-5 diagnosis.
Int J Clin Health Psychol. 2016 Sep-Dec;16(3):266-275. doi: 10.1016/j.ijchp.2016.03.001. Epub 2016 Jun 3.
5
Regional alterations in purkinje cell density in patients with autism.
PLoS One. 2014 Feb 24;9(2):e81255. doi: 10.1371/journal.pone.0081255. eCollection 2014.
6
Assessing behavioural and cognitive domains of autism spectrum disorders in rodents: current status and future perspectives.
Psychopharmacology (Berl). 2014 Mar;231(6):1125-46. doi: 10.1007/s00213-013-3268-5. Epub 2013 Sep 19.

本文引用的文献

1
Attention profiles in autistic children with and without comorbid hyperactivity and attention problems.
Acta Neuropsychiatr. 2008 Aug;20(4):207-15. doi: 10.1111/j.1601-5215.2008.00292.x.
3
Heterogeneity and homogeneity across the autism spectrum: the role of development.
J Am Acad Child Adolesc Psychiatry. 2009 May;48(5):471-473. doi: 10.1097/CHI.0b013e31819f6c0d.
5
Examining executive functioning in children with autism spectrum disorder, attention deficit hyperactivity disorder and typical development.
Psychiatry Res. 2009 Apr 30;166(2-3):210-22. doi: 10.1016/j.psychres.2008.02.005. Epub 2009 Mar 12.
6
Are executive control functions related to autism symptoms in high-functioning children?
Child Neuropsychol. 2009 Sep;15(5):425-40. doi: 10.1080/09297040802646983.
7
Understanding executive control in autism spectrum disorders in the lab and in the real world.
Neuropsychol Rev. 2008 Dec;18(4):320-38. doi: 10.1007/s11065-008-9077-7. Epub 2008 Oct 28.
9
Intra-individual variability in ADHD, autism spectrum disorders and Tourette's syndrome.
Neuropsychologia. 2008 Nov;46(13):3030-41. doi: 10.1016/j.neuropsychologia.2008.06.013. Epub 2008 Jun 21.
10
Head circumference and height in autism: a study by the Collaborative Program of Excellence in Autism.
Am J Med Genet A. 2006 Nov 1;140(21):2257-74. doi: 10.1002/ajmg.a.31465.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验