Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Corrensstrasse 3, D06466 Gatersleben, Germany.
Trends Plant Sci. 2011 May;16(5):273-81. doi: 10.1016/j.tplants.2011.02.002. Epub 2011 Mar 9.
Eukaryotic chromosomes occupy distinct territories within interphase nuclei. The arrangement of chromosome territories (CTs) is important for replication, transcription, repair and recombination processes. Our knowledge about interphase chromatin arrangement is mainly based on results from in situ labeling approaches. The phylogenetic affiliation of a species, cell cycle, differentiation status and environmental factors are all likely to influence interphase nuclear architecture. In this review we survey current data about relative positioning of CTs, somatic pairing of homologs, and sister chromatid alignment in meristematic and differentiated tissues, using data derived mainly from Arabidopsis thaliana, wheat (Triticum aestivum) and their relatives. We discuss morphological constraints and epigenetic impacts on nuclear architecture, the evolutionary stability of CT arrangements, and alterations of nuclear architecture during transcription and repair.
真核生物染色体在间期核中占据独特的区域。染色体区室（CT）的排列对于复制、转录、修复和重组过程很重要。我们对间期染色质排列的了解主要基于原位标记方法的结果。物种的系统发育关系、细胞周期、分化状态和环境因素都可能影响间期核结构。在这篇综述中，我们主要使用来自拟南芥、小麦（Triticum aestivum）及其亲缘种的数据，调查了 CT 相对位置、同源体体细胞配对以及有丝分裂和分化组织中姐妹染色单体排列的最新数据。我们讨论了对核结构的形态限制和表观遗传影响、CT 排列的进化稳定性以及转录和修复过程中核结构的改变。
