Charney D S, Krystal J H, Delgado P L, Heninger G R
Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06510.
Annu Rev Med. 1990;41:437-46. doi: 10.1146/annurev.me.41.020190.002253.
In the last few years there has been a marked increase in knowledge regarding the possible roles of serotonin neuronal dysfunction in the pathophysiology and treatment of anxiety and depressive disorders. During the same time period, new drugs with specific actions on serotonin function have become available for clinical testing. This review provides an update on the efficacy of serotonin-specific drugs for anxiety and depressive disorders.
在过去几年中,关于血清素神经元功能障碍在焦虑症和抑郁症的病理生理学及治疗中可能发挥的作用,人们的认识有了显著提高。在同一时期,对血清素功能具有特定作用的新药已可供临床测试。本综述提供了血清素特异性药物治疗焦虑症和抑郁症疗效的最新信息。