冰毒注射与注射吸毒者体内 HIV RNA 抑制更慢相关。
Crystal methamphetamine injection predicts slower HIV RNA suppression among injection drug users.
机构信息
British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, University of British Columbia, Vancouver, Canada.
出版信息
Addict Behav. 2011 Jul;36(7):762-3. doi: 10.1016/j.addbeh.2011.02.001. Epub 2011 Feb 13.
Abstract
We examined the impact of crystal methamphetamine injection on HIV RNA suppression among a prospective cohort of HIV-positive injection drug users initiating antiretroviral therapy. A multivariate Cox regression analysis found crystal methamphetamine injection to be negatively associated with viral load suppression (RH=0.63 [95% CI: 0.40-0.98]; p=0.039). This study is the first to our knowledge to demonstrate an association between crystal methamphetamine use and HIV RNA suppression.
摘要
我们研究了注射冰毒对开始接受抗逆转录病毒治疗的 HIV 阳性注射吸毒者队列中 HIV RNA 抑制的影响。多变量 Cox 回归分析发现，注射冰毒与病毒载量抑制呈负相关（RH=0.63[95%CI：0.40-0.98]；p=0.039）。据我们所知，这项研究首次证明了冰毒使用与 HIV RNA 抑制之间存在关联。
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