Department of Respiratory Medicine, Wenzhou Medical College Affiliated Second Hospital-Yuying Children's Hospital, Zhejiang, People's Republic of China.
J Pediatr. 2011 Aug;159(2):238-42.e1. doi: 10.1016/j.jpeds.2011.01.036. Epub 2011 Mar 12.
To examine the prevalence and correlates of nocturnal enuresis (NE) in primary school children, and to compare the prevalence of NE in children with and those without obstructive sleep apnea (OSA).
Parents of children aged 6-11 years completed a questionnaire eliciting information on sleep-related symptoms, demography, and family and past medical history. Children screened due to high risk for OSA, along with a randomly chosen low-risk group, underwent overnight polysomnography (PSG).
A total of 6147 children (3032 girls) were studied. The overall prevalence of NE (≥1 wet night/month) was 4.6% (6.7% of boys and 2.5% of girls). Boys had a significantly greater prevalence across all age groups. In 597 children (215 girls) who underwent PSG, the prevalence of NE was not greater in children with OSA, but was increased with increasing severity of OSA in girls only. Boys with NE had longer deep sleep duration. Sex and sleep-related symptoms were associated with NE.
This community-based study demonstrated a sex-associated prevalence of NE in relation to increasing OSA severity.
调查小学生夜间遗尿（NE）的患病率及其相关因素，并比较伴有和不伴有阻塞性睡眠呼吸暂停（OSA）的儿童的 NE 患病率。
6-11 岁儿童的家长填写了一份调查问卷，内容涉及与睡眠相关的症状、人口统计学、家庭和既往病史。由于存在 OSA 高风险而接受筛查的儿童，以及随机选择的低风险组儿童，均接受了整夜多导睡眠图（PSG）检查。
共研究了 6147 名儿童（3032 名女孩）。NE（≥1 个湿夜/月）的总体患病率为 4.6%（男孩为 6.7%，女孩为 2.5%）。男孩在所有年龄组的患病率均显著更高。在接受 PSG 检查的 597 名儿童（215 名女孩）中，OSA 患儿的 NE 患病率并不更高，但仅在女孩中，OSA 严重程度增加与 NE 患病率增加相关。有 NE 的男孩深度睡眠时间更长。性别和与睡眠相关的症状与 NE 相关。
这项基于社区的研究表明，与 OSA 严重程度增加相关的 NE 患病率存在性别关联。
