全范围复合超高灵敏光学微血管成像。
Full range complex ultrahigh sensitive optical microangiography.
机构信息
Department of Bioengineering, University of Washington, Seattle, Washington 98195, USA.
出版信息
Opt Lett. 2011 Mar 15;36(6):831-3. doi: 10.1364/OL.36.000831.
Abstract
This Letter presents a useful method that combines the full range complex Fourier domain optical coherence tomography (OCT) with the ultrahigh sensitive optical microangiography (OMAG) to achieve full range complex imaging of blood flow within microcirculatory tissue beds in vivo. We propose to use the fast scanning axis to realize the full range complex imaging, while using the slow axis to achieve OMAG imaging of blood flow. We demonstrate the proposed method by using a high speed 1310 nm OCT/OMAG system running at 92 kHz line scan rate to image the flow phantoms in vitro, and the blood flows in tissue beds in vivo.
摘要
这封信件提出了一种有用的方法，该方法结合了全范围复域光学相干断层扫描（OCT）和超高灵敏度的光学微血管造影术（OMAG），以实现活体微循环组织床内血流的全范围复域成像。我们建议使用快速扫描轴来实现全范围复域成像，同时使用慢轴来实现血流的 OMAG 成像。我们使用高速 1310nm OCT/OMAG 系统以 92kHz 的线扫描速率运行来对体外流动幻象和活体组织床内的血流进行成像，从而证明了该方法的可行性。
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