从柳珊瑚 Isis hippuris 中分离得到的 4 种新的多氧化甾醇。

Four new polyoxygenated gorgosterols from the gorgonian Isis hippuris.

机构信息

Department of Chemistry, Biology and Marine Science, University of the Ryukyus, Nishihara, Okinawa 903-0213, Japan.

出版信息

Nat Prod Res. 2011 Mar;25(6):585-91. doi: 10.1080/14786419.2010.485303.

DOI:10.1080/14786419.2010.485303

Abstract

Four new polyoxygenated steroids (1-4) together with four known ones (5-8) have been isolated from the gorgonian Isis hippuris. The structures of the new compounds have been elucidated by spectroscopic analysis and chemical conversion. All of the new steroids showed moderate cytotoxicity against cultured NBT-T2 cells.

摘要

从柳珊瑚 Isis hippuris 中分离得到了四个新的多氧化甾体化合物（1-4）和四个已知的甾体化合物（5-8）。通过光谱分析和化学转化，确定了新化合物的结构。所有新的甾体化合物对 NBT-T2 细胞均显示出中等的细胞毒性。