Sheu Jyh-Horng, Huang Long-Fei, Chen Shin-Pin, Yang Yi-Lea, Sung Ping-Jyun, Wang Guey-Horng, Su Jui-Hsin, Chao Chih-Hua, Hu Wan-Ping, Wang Jeh-Jeng
Department of Marine Resources, National Sun Yat-Sen University, Kaohsiung 804, Taiwan, Republic of China.
J Nat Prod. 2003 Jul;66(7):917-21. doi: 10.1021/np020602r.
Five novel (22R,23S,24S)-steroids, hippuristerones E-I (1-5), have been isolated from the gorgonian coral Isis hippuris. The structures of steroids 1-5 were deduced by extensive 1D and 2D NMR studies ((1)H, (13)C, (1)H-(1)H COSY, HMQC, HMBC, and NOESY experiments). The structure of 1 was further supported by molecular mechanics calculations.
从柳珊瑚类海柳（Isis hippuris）中分离出了五种新型的(22R,23S,24S)-甾体化合物，即马尿海柳甾酮E - I（1 - 5）。通过广泛的一维和二维核磁共振研究（氢谱、碳谱、氢-氢化学位移相关谱、异核单量子相干谱、异核多键相关谱和核Overhauser效应谱实验）推断出甾体化合物1 - 5的结构。分子力学计算进一步证实了化合物1的结构。
