Laboratory of Neural Injury and Repair, The Wadsworth Center, New York State Department of Health, PO Box 509, Empire State Plaza, Albany, NY 12201-0509, USA.
Clin Neurophysiol. 2011 Sep;122(9):1820-6. doi: 10.1016/j.clinph.2011.02.016. Epub 2011 Mar 15.
Brain-computer interface (BCI) technology might be useful for rehabilitation of motor function. This speculation is based on the premise that modifying the EEG will modify behavior, a proposition for which there is limited empirical data. The present study examined the possibility that voluntary modulation of sensorimotor rhythm (SMR) can affect motor behavior in normal human subjects.
Six individuals performed a cued-reaction task with variable warning periods. A typical variable foreperiod effect was associated with SMR desynchronization. SMR features that correlated with reaction times were then used to control a two-target cursor movement BCI task. Following successful BCI training, an uncued reaction time task was embedded within the cursor movement task.
Voluntarily increasing SMR beta rhythms was associated with longer reaction times than decreasing SMR beta rhythms.
Voluntary modulation of EEG SMR can affect motor behavior.
These results encourage studies that integrate BCI training into rehabilitation protocols and examine its capacity to augment restoration of useful motor function.
脑-机接口（BCI）技术可能对运动功能康复有用。这一推测基于这样一种前提，即改变脑电图（EEG）将改变行为，而这一命题的经验数据有限。本研究检验了自愿调制感觉运动节律（SMR）是否可以影响正常人体受试者的运动行为。
6 名个体在有不同预警期的情况下执行提示反应任务。典型的可变预备期效应与 SMR 去同步化相关。与反应时间相关的 SMR 特征随后被用于控制双目标光标运动 BCI 任务。在成功的 BCI 训练之后，在光标运动任务中嵌入了一个无提示反应时间任务。
与降低 SMRβ 节律相比，自愿增加 SMRβ 节律与更长的反应时间相关。
EEG SMR 的自愿调制可以影响运动行为。
这些结果鼓励将 BCI 训练纳入康复方案的研究，并检验其增强有用运动功能恢复的能力。
