三乙醇胺应用对蒽林诱导的银屑病炎症及治疗效果的影响。

The effect of triethanolamine application on anthralin-induced inflammation and therapeutic effect in psoriasis.

作者信息

Ramsay B, Lawrence C M, Bruce J M, Shuster S

机构信息

Department of Dermatology, Royal Victoria Infirmary, Newcastle-upon-Tyne, U.K.

出版信息

J Am Acad Dermatol. 1990 Jul;23(1):73-6. doi: 10.1016/0190-9622(90)70189-o.

DOI:10.1016/0190-9622(90)70189-o

PMID:2142172

Abstract

Twenty patients with chronic plaque psoriasis were treated with short-contact anthralin followed by 10% triethanolamine application to one side of the body and aqueous cream to the other. Anthralin-induced inflammation was inhibited on the triethanolamine-treated side whereas anthralin therapy had to be temporarily stopped in 18 patients on the aqueous cream side because of anthralin-induced inflammation. Therapeutic response was not different in the two sides. This study shows that anthralin-induced inflammation and its therapeutic effect can be dissociated.

摘要

20例慢性斑块状银屑病患者接受短程接触蒽林治疗，随后在身体一侧涂抹10%三乙醇胺，另一侧涂抹水性乳膏。在三乙醇胺治疗侧，蒽林诱导的炎症受到抑制，而在水性乳膏侧，18例患者因蒽林诱导的炎症不得不暂时停止蒽林治疗。两侧的治疗反应没有差异。这项研究表明，蒽林诱导的炎症及其治疗效果可以分离。