Department of Oral Pathology, Government Dental College and Hospital, Ahmedabad, India.
Indian Pediatr. 2011 Sep;48(9):719-21. doi: 10.1007/s13312-011-0113-y.
This case-control study was conducted to determine the protective role of salivary secretory immunoglobulin A (SIgA) levels in the unstimulated whole saliva of dental caries active (Group I and II) and caries free children (Group III). Thirty children aged 4-8 years were selected. Their DMFT (Decayed Missing Filled teeth for permanent teeth) and/or df-t (decayed, filled teeth for deciduous teeth) scores were determined and the salivary SIgA levels were measured using Immunoturbidometry. SIgA levels of all three groups were in the the normal range of 4-30 mg/dL. The SIgA levels for both Group I and II were less than that in Group III (P=0.018 and P=0.0013, respectively).
本病例对照研究旨在确定唾液分泌型免疫球蛋白 A(SIgA)水平在龋齿活跃(I 组和 II 组)和无龋儿童(III 组)未刺激全唾液中的保护作用。选择了 30 名年龄在 4-8 岁的儿童。确定了他们的 DMFT(恒牙龋齿缺失填充)和/或 df-t(乳牙龋齿填充)评分,并使用免疫比浊法测量了唾液 SIgA 水平。三组的 SIgA 水平均在 4-30mg/dL 的正常范围内。I 组和 II 组的 SIgA 水平均低于 III 组(P=0.018 和 P=0.0013)。