Rustin M H, Robinson T W, Dowd P M
Department of Dermatology, University College and Middlesex School of Medicine, Middlesex Hospital, London, U.K.
Br J Dermatol. 1990 Jul;123(1):119-24. doi: 10.1111/j.1365-2133.1990.tb01832.x.
Three patients are described who developed numerous pinhead sized pustules within areas of a widespread toxic erythema. The eruption was precipitated by food poisoning in one patient, a suspected, but blood-culture-negative septicaemia in another and in the third patient, by a cephalosporin. This self-limiting syndrome consists of fever, a pustular and erythematous eruption, a neutrophil leucocytosis, subcorneal and spongiform pustules but without a history of psoriasis. We believe that this entity of toxic pustuloderma represents a severe form of toxic erythema.
本文描述了三名患者,他们在广泛的中毒性红斑区域内出现了大量针头大小的脓疱。一名患者的皮疹由食物中毒引发,另一名患者疑似败血症但血培养阴性,第三名患者的皮疹由头孢菌素引发。这种自限性综合征包括发热、脓疱性和红斑性皮疹、中性粒细胞增多、角层下和海绵状脓疱,但无银屑病病史。我们认为这种中毒性脓疱性皮炎是中毒性红斑的一种严重形式。