Division of Neonatology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USA.
J Perinatol. 2011 Apr;31 Suppl 1:S29-34. doi: 10.1038/jp.2010.172.
The intestinal microbiota normally exists in a commensal and/or symbiotic relationship with the host. In the past few years, emerging technologies derived largely from the Human Genome Project have been applied to evaluating the intestinal microbiota and new discoveries using these techniques have prompted new initiatives such as the Human Microbiome Roadmap designed to evaluate the role of the intestinal microbiome in health and disease. In this review, we wish to focus on some new developments in this area and discuss some of the effects of medical manipulations such as antibiotics, probiotics, prebiotics and C-section versus vaginal delivery on the intestinal microbiota.
肠道微生物群通常与宿主保持共生或共栖关系。在过去的几年中，源自人类基因组计划的新兴技术被应用于评估肠道微生物群，这些技术的新发现促使了新的计划，如人类微生物组计划，旨在评估肠道微生物群在健康和疾病中的作用。在这篇综述中，我们希望关注该领域的一些新进展，并讨论一些医疗操作（如抗生素、益生菌、益生元以及剖宫产与阴道分娩）对肠道微生物群的影响。
