H-2 限制性细胞毒性 T 细胞对巨噬细胞单层的特异性吸附。
Specific adsorption of H-2-restricted cytotoxi T cells to macrophage monolayers.
作者信息
Kees U, Müllbacher A, Blanden R V
出版信息
J Exp Med. 1978 Dec 1;148(6):1711-5. doi: 10.1084/jem.148.6.1711.
Abstract
These experiments tested whether Tc cells specific for foreign antigen (X) plus self H-2 adsorbed to macrophage monolayers displaying (a) X with allogeneic H-2; (B) self H-2 alone; (c) X plus self H-2. Specific adsorption occurred only in case (c), a result compatible with altered self and requiring further operational assumptions in dual recognition models.
摘要
这些实验检测了对异源抗原（X）加上自身H-2特异的Tc细胞，是否吸附于展示以下情况的巨噬细胞单层：（a）带有同种异体H-2的X；（B）单独的自身H-2；（c）X加上自身H-2。特异性吸附仅在情况（c）中出现，这一结果与自身改变相符，并且在双重识别模型中需要进一步的操作假设。
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Cell-medicated cytotoxicity against ectromelia virus-infected target cells. III. Role of the H-2 gene complex.细胞介导的针对感染痘苗病毒的靶细胞的细胞毒性。III. H-2基因复合体的作用。
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H-2 compatibility requirement for virus-specific T-cell-mediated cytolysis. The H-2K structure involved is coded by a single cistron defined by H-2Kb mutant mice.病毒特异性T细胞介导的细胞溶解对H-2相容性的要求。所涉及的H-2K结构由H-2Kb突变小鼠定义的单个顺反子编码。
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