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交通暴露增加与不良出生结局:澳大利亚一项前瞻性队列研究。

Increased traffic exposure and negative birth outcomes: a prospective cohort in Australia.

机构信息

School of Public Health & Institute of Health and Biomedical Innovation, Queensland University of Technology, Kelvin Grove, Queensland, Australia.

出版信息

Environ Health. 2011 Apr 1;10:26. doi: 10.1186/1476-069X-10-26.

DOI:10.1186/1476-069X-10-26
PMID:21453550
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3083331/
Abstract

BACKGROUND

Pregnant women exposed to traffic pollution have an increased risk of negative birth outcomes. We aimed to investigate the size of this risk using a prospective cohort of 970 mothers and newborns in Logan, Queensland.

METHODS

We examined two measures of traffic: distance to nearest road and number of roads around the home. To examine the effect of distance we used the number of roads around the home in radii from 50 to 500 metres. We examined three road types: freeways, highways and main roads.

RESULTS

There were no associations with distance to road. A greater number of freeways and main roads around the home were associated with a shorter gestation time. There were no negative impacts on birth weight, birth length or head circumference after adjusting for gestation. The negative effects on gestation were largely due to main roads within 400 metres of the home. For every 10 extra main roads within 400 metres of the home, gestation time was reduced by 1.1% (95% CI: -1.7, -0.5; p-value = 0.001).

CONCLUSIONS

Our results add weight to the association between exposure to traffic and reduced gestation time. This effect may be due to the chemical toxins in traffic pollutants, or because of disturbed sleep due to traffic noise.

摘要

背景

暴露于交通污染中的孕妇发生不良生育结局的风险增加。我们旨在通过昆士兰州洛根的 970 名母亲及其新生儿的前瞻性队列研究来调查这种风险的大小。

方法

我们研究了两种交通措施:距最近道路的距离和住所周围道路的数量。为了研究距离的影响,我们使用住所周围道路数量作为半径为 50 至 500 米的指标。我们研究了三种道路类型:高速公路、公路和主要道路。

结果

与道路距离无关。住所周围有更多的高速公路和主要道路与较短的妊娠时间相关。在调整了妊娠时间后,对出生体重、出生长度或头围没有负面影响。对妊娠的负面影响主要是由于住所周围 400 米范围内的主要道路造成的。住所周围每增加 10 条额外的主要道路,妊娠时间会减少 1.1%(95%CI:-1.7,-0.5;p 值=0.001)。

结论

我们的研究结果进一步证实了暴露于交通与缩短妊娠时间之间的关联。这种影响可能是由于交通污染物中的化学毒素,或者是由于交通噪音导致的睡眠受到干扰。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4243/3083331/928c1ae6e384/1476-069X-10-26-7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4243/3083331/73115a53c52b/1476-069X-10-26-1.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4243/3083331/928c1ae6e384/1476-069X-10-26-7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4243/3083331/73115a53c52b/1476-069X-10-26-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4243/3083331/618719de9891/1476-069X-10-26-2.jpg
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