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在感染人巨细胞病毒的WI-38细胞中,由重复的二分结构组成的染色质模式。

Chromatin pattern consisting of repeating bipartite structures in WI-38 cells infected with human cytomegalovirus.

作者信息

Kierszenbaum A L, Huang E S

出版信息

J Virol. 1978 Nov;28(2):661-4. doi: 10.1128/JVI.28.2.661-664.1978.

Abstract

A novel chromatin structural pattern displaying bipartite and oblate ellipsoid structures orderly arranged along a fiber axis has been observed in WI-38 cells infected with human cytomegalovirus. This chromatin type coexists with chromatin fibers showing conventional nucleosomes. Each bipartite-oblate structure is 40 nm in length, about four times as long as an ordinary nucleosome, and the number of these structures per micrometer (11/micrometer) is clearly less than that of typical cellular nucleosomes (32/micrometer).

摘要

在感染人巨细胞病毒的WI-38细胞中,观察到一种新型染色质结构模式,其显示出二分体和扁椭圆形结构沿纤维轴有序排列。这种染色质类型与显示传统核小体的染色质纤维共存。每个二分体-扁椭圆形结构长度为40纳米,约为普通核小体长度的四倍,每微米这些结构的数量(11/微米)明显少于典型细胞内核小体的数量(32/微米)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a842/354313/1a92707241c9/jvirol00203-0248-a.jpg

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