Department of Microbiology, East Tennessee State University, James H. Quillen College of Medicine, Johnson City, TN 37614-1708, USA.
Microbes Infect. 2011 Jul;13(7):649-62. doi: 10.1016/j.micinf.2011.03.004. Epub 2011 Mar 31.
Under stress, chlamydiae can enter a non-infectious but viable state termed persistence. In the absence of a tractable genetic system, persistence induction provides an important experimental tool with which to study these fascinating organisms. This review will discuss examples of: i) persistence studies that have illuminated critical chlamydiae/host interactions; and ii) novel persistence models that will do so in the future.
在应激条件下，衣原体可以进入一种非感染但有活力的状态，称为持续存在。在缺乏可行的遗传系统的情况下，持续存在的诱导为研究这些迷人的生物体提供了一个重要的实验工具。这篇综述将讨论以下几个方面：i）阐明关键衣原体/宿主相互作用的持续存在研究；和 ii）未来将这样做的新型持续存在模型。
