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宿主与病原体界面:microRNAs 是疾病结局的调节剂。

Host and pathogen interface: microRNAs are modulators of disease outcome.

机构信息

Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA; Arkansas Children's Research Institute, Little Rock, AR, USA; Arkansas Children's Nutrition Center, Little Rock, AR, USA.

Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA; Arkansas Children's Research Institute, Little Rock, AR, USA; Arkansas Children's Nutrition Center, Little Rock, AR, USA.

出版信息

Microbes Infect. 2018 Aug-Sep;20(7-8):410-415. doi: 10.1016/j.micinf.2017.08.002. Epub 2017 Sep 7.

Abstract

Chlamydiae are a group of intracellular bacterium that infect a range of hosts and are responsible for the most common sexual transmitted infections, which could be the result of a plethora of factors leading to varied pathological outcomes. This review aims to show that Chlamydia possibly manipulates host defenses through microRNAs interaction.

摘要

衣原体是一组感染多种宿主的细胞内细菌,是最常见的性传播感染的病原体,其发病机制可能涉及多种因素导致不同的病理结果。本综述旨在表明衣原体可能通过 microRNAs 相互作用来操纵宿主防御。

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