根管冲洗剂及其组合对粪肠球菌的pH值、有效氯含量和抗菌活性评估
Evaluation of pH, available chlorine content, and antibacterial activity of endodontic irrigants and their combinations against Enterococcus faecalis.
作者信息
Guerreiro-Tanomaru Juliane M, Morgental Renata D, Flumignan Danilo L, Gasparini Fabricia, Oliveira José E, Tanomaru-Filho Mário
机构信息
Department of Restorative Dentistry, Araraquara Dental School, UNESP, Univ Estadual Paulista, Araraquara, SP, Brazil.
出版信息
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011 Jul;112(1):132-5. doi: 10.1016/j.tripleo.2011.01.009. Epub 2011 Apr 1.
OBJECTIVES
The objectives of this study were to evaluate pH, available chlorine content, and antibacterial activity of endodontic irrigants and their combinations.
STUDY DESIGN
The pH and chlorine content of sodium hypochlorite (NaOCl) were analyzed pure and in combination with 10% citric acid (CA) and apple vinegar (AV). The antibacterial effect of the following solutions was measured by direct contact test against Enterococcus faecalis: 2.5% NaOCl, 2.5% NaOCl +10% CA (7:3), 2.5% NaOCl + AV (5:5), 10% CA, and AV. Sterile saline was used as control. The colony-forming units were determined by serial decimal dilutions.
RESULTS
The combination of 2.5% NaOCl with CA or AV lowered the pH and the chlorine content. NaOCl, alone or in combination was able to eliminate E. faecalis in 30 seconds, and CA, after 10 minutes. AV promoted reduction (32.2%) after 10 minutes.
CONCLUSIONS
NaOCl with acidic solutions lowered the pH and the chlorine content, but did not alter its antibacterial effect.
目的
本研究的目的是评估根管冲洗剂及其组合的pH值、有效氯含量和抗菌活性。
研究设计
分析了纯次氯酸钠（NaOCl）以及与10%柠檬酸（CA）和苹果醋（AV）组合后的pH值和氯含量。通过对粪肠球菌的直接接触试验，测定了以下溶液的抗菌效果：2.5% NaOCl、2.5% NaOCl + 10% CA（7:3）、2.5% NaOCl + AV（5:5）、10% CA和AV。使用无菌生理盐水作为对照。通过连续十进制稀释法确定菌落形成单位。
结果
2.5% NaOCl与CA或AV的组合降低了pH值和氯含量。单独使用或组合使用的NaOCl能够在30秒内消除粪肠球菌，而CA在10分钟后能消除。AV在10分钟后促进了（32.2%）的减少。
结论
NaOCl与酸性溶液组合降低了pH值和氯含量，但未改变其抗菌效果。
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