Department of Pediatrics, Dr. Behcet Uz Child Disease and Pediatric Surgery Training and Research Hospital, Izmir, Turkey.
Mycopathologia. 2011 Sep;172(3):237-9. doi: 10.1007/s11046-011-9418-6. Epub 2011 Apr 3.
Candida ciferrii, which is known as an agent of superficial yeast infection and onychomycosis, has rarely been isolated as an agent of candidemia. Limited reports have suggested different patterns of antifungal sensitivity. We report a rare candidemia case caused by c.ciferrii in an 8-year-old child in which isolated candida species were resistant to amphotericin-B (MIC > 1 μg/ml), fluconazole, (MIC ≥ 64 μg/ml), caspofungin (MIC ≥ 32 μg/ml), and anidulafungin (MIC ≥ 32 μg/ml) but sensitive to voriconazole (MIC ≤ 0.12 μg/ml). As far as we aware, this was the first recorded C. ciferrii candidemia case in children.
棘状白假丝酵母菌是一种已知的浅部酵母感染和甲真菌病的病原体，很少被分离为菌血症的病原体。有限的报告表明了不同的抗真菌药物敏感性模式。我们报告了一例由棘状白假丝酵母菌引起的罕见 8 岁儿童菌血症病例，分离出的念珠菌对两性霉素 B（MIC＞1μg/ml）、氟康唑（MIC≥64μg/ml）、卡泊芬净（MIC≥32μg/ml）和阿尼芬净（MIC≥32μg/ml）耐药，但对伏立康唑（MIC≤0.12μg/ml）敏感。据我们所知，这是首例儿童棘状白假丝酵母菌菌血症病例。
