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CT引导下立体定向技术对肝脏肿瘤进行射频消融的靶向准确性。

Targeting accuracy of CT-guided stereotaxy for radiofrequency ablation of liver tumours.

作者信息

Widmann Gerlig, Schullian Peter, Haidu Marion, Fasser Martin, Bale Reto

机构信息

Department of Microinvasive Therapy, Medical University of Innsbruck, Innsbruck, Austria.

出版信息

Minim Invasive Ther Allied Technol. 2011 Jul;20(4):218-25. doi: 10.3109/13645706.2010.533923. Epub 2011 Apr 6.

DOI:10.3109/13645706.2010.533923
PMID:21469968
Abstract

The targeting accuracy during CT-guided stereotactic radiofrequency ablation (SRFA) of liver tumours was evaluated in a clinical study. Patients under general anaesthesia were immobilized using a vacuum cushion and respiratory motion control was based on temporary disconnections of the endotracheal tube. An optical-based navigation system was used for 3D trajectory planning and needle placement via a stereotactic aiming device. A control CT with the needles in place was fused with the planning CT for accuracy evaluation. Sub-analysis was performed for "location" (liver segments II-VIII), "approach" (intercostal or transabdominal), "properties" (clear parenchymal, subcapsular, subphrenic, fat, and subphrenic plus fat), and "path length". In 20 patients with 35 liver lesions, a total of 145 needles were placed with mean (±SD) lateral errors of 3.6 ± 2.5 mm at the needle tip, angular errors of 1.3° ± 1.2°, and longitudinal errors at the needle tip of -7.4 ± 6.2 mm. No puncture-related complications were noted. No significant differences of angular errors between segments, approach and properties were recorded. Long paths correlated with smaller angular errors. CT-guided stereotaxy can be considered safe and provided precise multiple needle placement for SRFA of liver lesions at arbitrary trajectories in various segments and locations.

摘要

一项临床研究评估了CT引导下肝肿瘤立体定向射频消融术(SRFA)的靶向准确性。全身麻醉下的患者使用真空垫固定,呼吸运动控制基于气管插管的临时断开。使用基于光学的导航系统通过立体定向瞄准装置进行三维轨迹规划和针的放置。将针到位后的对照CT与规划CT融合以进行准确性评估。对“位置”(肝段II - VIII)、“入路”(肋间或经腹)、“性质”(实质清晰、包膜下、膈下、脂肪及膈下加脂肪)和“路径长度”进行亚分析。在20例有35个肝病灶的患者中,共放置了145根针,针尖端的平均(±标准差)横向误差为3.6±2.5mm,角度误差为1.3°±1.2°,针尖端的纵向误差为 - 7.4±6.2mm。未观察到与穿刺相关的并发症。各肝段、入路和性质之间的角度误差无显著差异。长路径与较小的角度误差相关。CT引导的立体定向术可被认为是安全的,并可为各段和不同位置的肝病灶SRFA以任意轨迹精确放置多根针。

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