Department of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, University of Athens, Panepistimioupolis, 15771, Athens, Greece.
Curr Pharm Des. 2011;17(13):1267-90. doi: 10.2174/138161211795703807.
Natural products and their derivatives have historically been invaluable as a source of therapeutic agents and have contributed to the discovery of antimicrobial agents. However, today with the development of drug-resistant strains, new scaffolds and new sources of bioactive compounds are needed. To this end, plant derived natural resins are reviewed for their potential application as antimicrobial agents. Natural gums, extracts of the whole resins, as well as specific extracts, fractions, essential oils and isolated compounds from the above resins are discussed in terms of their antifungal, antibacterial, and antiprotozoal activity.
天然产物及其衍生物一直是治疗药物的宝贵来源，为抗菌药物的发现做出了贡献。然而，如今随着耐药菌株的出现，需要新的骨架和生物活性化合物的新来源。为此，本文综述了植物来源的天然树脂作为抗菌剂的潜在应用。讨论了天然树胶、整个树脂的提取物以及特定提取物、馏分、上述树脂的精油和分离化合物在抗真菌、抗细菌和抗原生动物方面的活性。
