Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai, P. R. China.
Planta Med. 2011 Sep;77(14):1617-22. doi: 10.1055/s-0030-1270969. Epub 2011 Apr 6.
Three new limonoids (toonaciliatins N-P, 1-3)and four new pimaradiene-type diterpenoids(toonacilidins A-D, 4-7) were isolated from the leaves and twigs of Toona ciliata Roem. var. yunnanensis.Their structures were elucidated on the basis of spectroscopic methods. Toonacilidin B(5)showed moderate inhibitory activity against H. pylori-SS1 with an MIC of 50 μg/mL.
从云南香椿的叶和嫩枝中分离得到了三个新的柠檬苦素(香椿宁 N-P,1-3)和四个新的贝壳杉二萜(香椿宁 A-D,4-7)。根据光谱方法阐明了它们的结构。香椿宁 B(5)对 H. pylori-SS1 表现出中等抑制活性,MIC 为 50μg/mL。