Department of Preventive Medicine and Community Health, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.
Cancer Epidemiol. 2011 Aug;35(4):342-4. doi: 10.1016/j.canep.2011.01.010. Epub 2011 Apr 6.
To better understand the picture of premature death from oral cancer, we estimated years of life lost (YLL) and average years of life lost (AYLL) of this cancer for the years 1995 and 2005 in Japan.
We obtained the mortality data for 5-year age groups from the Vital Statistics of Japan for the years 1995 and 2005, an interval of 10 years. Age-standardized rates (ASRs) per 100,000 persons were calculated for each subset of oral cancer. We estimated YLL and AYLL according to life tables in Japan to reflect premature mortality.
For both men and women combined, 4099 and 5679 deaths due to oral cancer were recorded for the years 1995 and 2005. In men, cancer of tongue, oropharynx, and hypopharynx were the most frequently observed anatomic sites. We observed a total of 51,339.1 years of life lost in 1995 and 68,630.4 years in 2005, corresponding to an overall AYLL for all oral cancer deaths combined of 17.2 and 16.5 years earlier than life expectancy, respectively. The greatest AYLL was seen for deaths from nasopharyngeal cancer, with AYLL of 21.1 years in 1995 and 20.3 years in 2005. In women, cancer of the tongue and gum were the most affected anatomic sites. Total numbers of YLL were 18,884.8 years in 1995 and 24,765.7 in 2005, corresponding to an overall AYLL of 16.9 and 16.2 years earlier than life expectancy. The greatest AYLL was seen for deaths from nasopharyngeal cancer, with AYLL of 22.4 years and 20.4 years in 1995 and 2005, respectively.
The present study shows that cancer of pharynx, tongue, and gum were the most frequent oral cancers in both sexes in both 1995 and 2005, and responsible for a remarkable number of years of life expectancy lost. Deaths due to those cancer sites occurred about 16-21 years earlier than expected in men, and 14-22 years in women.
为了更好地了解口腔癌导致的过早死亡情况，我们估算了日本 1995 年和 2005 年口腔癌的寿命损失年（years of life lost，YLL）和平均寿命损失年（average years of life lost，AYLL）。
我们从日本的人口动态统计数据中获取了 1995 年和 2005 年每 5 岁年龄组的死亡率数据，这两个年份之间相隔 10 年。为每个口腔癌亚组计算了每 100,000 人标准化的死亡率（age-standardized rates，ASR）。我们根据日本的生命表来估算 YLL 和 AYLL，以反映过早死亡的情况。
1995 年和 2005 年因口腔癌导致的死亡人数分别为 4099 人和 5679 人。在男性中，舌、口咽和下咽癌是最常见的解剖部位。我们总共在 1995 年观察到 51,339.1 年的生命损失，在 2005 年观察到 68,630.4 年的生命损失，这对应于所有口腔癌死亡的整体 AYLL，分别比预期寿命早 17.2 年和 16.5 年。鼻咽癌症的 AYLL 最大，1995 年为 21.1 年，2005 年为 20.3 年。在女性中，舌癌和牙龈癌是最常见的解剖部位。1995 年 YLL 总数为 18,884.8 年，2005 年为 24,765.7 年，这对应于整体 AYLL，分别比预期寿命早 16.9 年和 16.2 年。鼻咽癌症的 AYLL 最大，1995 年为 22.4 年，2005 年为 20.4 年。
本研究表明，在 1995 年和 2005 年，口咽、舌和牙龈癌是男女中最常见的口腔癌，导致了大量的预期寿命损失。这些部位的癌症导致的死亡在男性中比预期早 16-21 年，在女性中早 14-22 年。
