Angiology. 2011 May;62(4):285-90. doi: 10.1177/0003319711399571.
Polycystic ovary syndrome (PCOS) is a common disorder in women of reproductive age, affecting around 10% of them. Polycystic ovary syndrome is considered to be related to increased risk for type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). There are 2 definitions for PCOS: one adopted in 1990 (classical PCOS with phenotypes A and B) and the other in 2003 (Rotterdam criteria with 4 phenotypes A to D). The latter is a wider definition including the 1990 phenotypes. There is mounting data suggesting that phenotypes C and D are not actually related to increased CVD risk, and thus screening for CVD risk factors of intervening for primary CVD prevention in young women is not cost-effective. There is an increasing number of suggestions to return to the 1990 criteria plus some metabolic parameters to identify real CVD risk in this population. However, such a strategy needs verification by large, prospective studies.
多囊卵巢综合征（PCOS）是育龄妇女的一种常见疾病，影响约 10%的妇女。多囊卵巢综合征被认为与 2 型糖尿病（T2DM）和心血管疾病（CVD）的风险增加有关。多囊卵巢综合征有 2 种定义：1990 年采用的一种（有表型 A 和 B 的经典多囊卵巢综合征）和 2003 年采用的另一种（有 4 种表型 A 到 D 的鹿特丹标准）。后者是一种更广泛的定义，包括 1990 年的表型。越来越多的数据表明，表型 C 和 D 实际上与 CVD 风险增加无关，因此对年轻女性进行 CVD 危险因素筛查以进行原发性 CVD 预防并不具有成本效益。越来越多的建议是回到 1990 年的标准加上一些代谢参数，以确定该人群的真正 CVD 风险。然而，这种策略需要通过大型前瞻性研究来验证。
