Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455, USA.
IEEE Trans Biomed Eng. 2011 Jul;58(7):1918-31. doi: 10.1109/TBME.2011.2139210. Epub 2011 Apr 7.
Unlocking the dynamic inner workings of the brain continues to remain a grand challenge of the 21st century. To this end, functional neuroimaging modalities represent an outstanding approach to better understand the mechanisms of both normal and abnormal brain functions. The ability to image brain function with ever increasing spatial and temporal resolution has made a significant leap over the past several decades. Further delineation of functional networks could lead to improved understanding of brain function in both normal and diseased states. This paper reviews recent advancements and current challenges in dynamic functional neuroimaging techniques, including electrophysiological source imaging, multimodal neuroimaging integrating fMRI with EEG/MEG, and functional connectivity imaging.
探索大脑的动态内部运作仍然是 21 世纪的重大挑战。为此，功能神经影像学方法是更好地理解正常和异常大脑功能机制的杰出途径。在过去几十年中，功能成像技术在提高空间和时间分辨率方面取得了重大飞跃。进一步描绘功能网络可以促进对正常和疾病状态下大脑功能的理解。本文综述了动态功能神经影像学技术的最新进展和当前挑战，包括电生理源成像、将 fMRI 与 EEG/MEG 相结合的多模态神经影像学以及功能连接成像。
