Wolfsberg Tyra G
Curr Protoc Hum Genet. 2011 Apr;Chapter 18:Unit18.5. doi: 10.1002/0471142905.hg1805s69.
This unit includes a basic protocol with an introduction to the Map Viewer, describing how to perform a simple text-based search of genome annotations to view the genomic context of a gene, navigate along a chromosome, zoom in and out, and change the displayed maps to hide and show information. It also describes some of NCBI's sequence-analysis tools, which are provided as links from the Map Viewer. The alternate protocols describe different ways to query the genome sequence, and also illustrate additional features of the Map Viewer. Alternate Protocol 1 shows how to perform and interpret the results of a BLAST search against the human genome. Alternate Protocol 2 demonstrates how to retrieve a list of all genes between two STS markers. Finally, Alternate Protocol 3 shows how to find all annotated members of a gene family.
本单元包括一个基本协议，其中介绍了地图查看器，描述了如何对基因组注释进行基于文本的简单搜索，以查看基因的基因组背景、沿着染色体导航、放大和缩小以及更改显示的图谱以隐藏和显示信息。它还介绍了一些NCBI的序列分析工具，这些工具以链接形式从地图查看器提供。替代协议描述了查询基因组序列的不同方法，还展示了地图查看器的其他功能。替代协议1展示了如何对人类基因组进行BLAST搜索并解释结果。替代协议2演示了如何检索两个STS标记之间所有基因的列表。最后，替代协议3展示了如何找到一个基因家族的所有注释成员。
