University of Pittsburgh School of Medicine, Department of Psychiatry, Western Psychiatric Institute and Clinic, 3811 O'Hara Street, Pittsburgh, PA 15213, USA.
Addict Behav. 2011 Aug;36(8):861-4. doi: 10.1016/j.addbeh.2011.03.001. Epub 2011 Mar 9.
Sleep disturbance may affect smoking cessation efforts. We describe sleep changes across three months among women in a smoking cessation program and tested whether sleep disturbances at baseline and 1 month post-quit attempt predicted smoking status at three months.
Participants (N=322) were women in a randomized, clinical trial for smoking cessation. Sleep disturbances, as well as, insomnia, drowsiness, and sleep quality were evaluated prior to and during three months of cessation treatment. Repeated measures mixed models evaluated change in sleep over time by smoking outcome status. Logistic regression analyses determined whether sleep disturbances at baseline and 1 month post-quit were associated with smoking status at 3 months.
Sleep disturbances were reported by more than 25% of women. Drowsiness, insomnia, and sleep quality changed over time. However, contrary to our hypotheses, none of the sleep variables at either baseline or 1 month post-quit attempt was associated with relapse (p's>.05).
Although mild to severe drowsiness was reported by more women who relapsed than those who remained abstinent, none of the sleep disturbance symptoms predicted smoking relapse. Given high rates of sleep disturbances among women smokers, better prospective evaluations of the relationship of sleep disturbances to smoking cessation treatment outcome are needed.
睡眠障碍可能会影响戒烟努力。我们描述了戒烟计划中女性在三个月内的睡眠变化，并测试了基线和戒烟尝试后 1 个月的睡眠障碍是否预测了三个月时的吸烟状况。
参与者（N=322）为戒烟随机临床试验中的女性。在戒烟治疗的三个月内，评估了睡眠障碍以及失眠、嗜睡和睡眠质量。重复测量混合模型通过吸烟结果状态评估睡眠随时间的变化。逻辑回归分析确定基线和戒烟尝试后 1 个月的睡眠障碍是否与 3 个月时的吸烟状况相关。
超过 25%的女性报告有睡眠障碍。嗜睡、失眠和睡眠质量随时间变化。然而，与我们的假设相反，基线或戒烟尝试后 1 个月的任何睡眠变量都与复吸无关（p>.05）。
尽管嗜睡的女性比保持戒烟的女性更常见，但报告的复吸者中，没有一种睡眠障碍症状可以预测吸烟复发。鉴于女性吸烟者中睡眠障碍的发生率较高，需要更好地前瞻性评估睡眠障碍与戒烟治疗结果之间的关系。
