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经肛门入路行全直肠系膜切除术在猪模型中的应用。

Ileorectal bypass performed entirely through a transanal route in a porcine model.

机构信息

Surgical Endoscopy Unit, Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy.

出版信息

Surg Endosc. 2011 Sep;25(9):3022-7. doi: 10.1007/s00464-011-1664-7. Epub 2011 Apr 12.

DOI:10.1007/s00464-011-1664-7
PMID:21484531
Abstract

BACKGROUND

Natural orifice transluminal endoscopic surgery (NOTES), a new frontier of minimally invasive surgery, uses the body's natural orifices to create an access for surgical procedures. This study aimed to verify the technical feasibility of ileorectal bypass performed entirely through a transanal access.

METHODS

The procedure was performed on 10 domestic pigs, after which they were killed. A transanal endoscopic microsurgery (TEM) device and endoscopic and laparoscopic instruments were used.

RESULTS

The findings demonstrated that an ileorectal bypass through a transanal access is feasible. The principal steps of a standardized transanal procedure are as follows: confirm a rectal perforation above the peritoneal reflection, perform peritoneoscopy using a standard gastroscope, grasp the small bowel with retrieval forceps and pull it through the rectal hole, suture the ileum and the rectum together using a TEM device, open the ileal loop, and perform endoscopic exploration. Satisfactory anastomosis and no signs of procedure-related complications were confirmed by a post procedure laparotomy.

CONCLUSIONS

Ileorectal bypass through a transanal access is technically feasible in a porcine model, and although still at an experimental stage, it could become a surgical option for treating some types of colonic strictures.

摘要

背景

经自然腔道内镜手术(NOTES)是微创外科的一个新领域,利用人体的自然腔道进行手术操作。本研究旨在验证经肛门入路完全进行回肠直肠旁路术的技术可行性。

方法

该手术在 10 只国内猪中进行,之后将其处死。使用经肛门内镜微创手术(TEM)设备和内镜及腹腔镜器械。

结果

研究结果表明,经肛门入路进行回肠直肠旁路术是可行的。标准化经肛门手术的主要步骤如下:确认直肠穿孔位于腹膜反射之上,使用标准胃镜进行腹腔镜检查,用取物钳抓住小肠并将其从直肠孔中拉出,使用 TEM 设备将回肠和直肠缝合在一起,打开回肠袢,并进行内镜探查。剖腹探查证实吻合满意,无与手术相关的并发症迹象。

结论

在猪模型中,经肛门入路进行回肠直肠旁路术在技术上是可行的,尽管仍处于实验阶段,但它可能成为治疗某些类型结肠狭窄的一种手术选择。

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本文引用的文献

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Surg Endosc. 2008 Feb;22(2):348-51. doi: 10.1007/s00464-007-9659-0. Epub 2007 Nov 20.
2
Dual-port distal pancreatectomy using a prototype endoscope and endoscopic stapler: a natural orifice transluminal endoscopic surgery (NOTES) survival study in a porcine model.使用原型内窥镜和内镜吻合器的双端口远端胰腺切除术:猪模型中的经自然腔道内镜手术(NOTES)生存研究
Endoscopy. 2007 Oct;39(10):881-7. doi: 10.1055/s-2007-966908.
3
Self-expanding metal stents in malignant colonic obstruction: have we covered all angles?
自膨式金属支架在恶性结肠梗阻中的应用:我们是否已全面考虑?
Gastrointest Endosc. 2007 Nov;66(5):937-9. doi: 10.1016/j.gie.2007.07.003.
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Self-expanding metal stents as nonsurgical palliative therapy for malignant colonic obstruction: time to change the standard of care?自膨式金属支架作为恶性结肠梗阻的非手术姑息治疗:是时候改变治疗标准了吗?
Gastrointest Endosc. 2007 Nov;66(5):928-30. doi: 10.1016/j.gie.2007.06.053.
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Feasibility of radical sigmoid colectomy performed as natural orifice translumenal endoscopic surgery (NOTES) using transanal endoscopic microsurgery.经肛门内镜显微手术作为自然腔道内镜手术(NOTES)实施根治性乙状结肠切除术的可行性。
Surg Endosc. 2007 Oct;21(10):1870-4. doi: 10.1007/s00464-007-9552-x. Epub 2007 Aug 21.
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Stents for palliation of obstructive metastatic colon cancer: impact on management and chemotherapy administration.用于缓解梗阻性转移性结肠癌的支架:对治疗管理和化疗给药的影响。
Arch Surg. 2007 Jul;142(7):619-23; discussion 623. doi: 10.1001/archsurg.142.7.619.
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An innovative, safe and sterile sigmoid access (ISSA) for NOTES.一种用于NOTES的创新、安全且无菌的乙状结肠入路(ISSA)
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Surg Endosc. 2007 Apr;21(4):672-6. doi: 10.1007/s00464-006-9124-5. Epub 2007 Feb 7.
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