Univ Paris Diderot, Sorbonne Paris Cité, Assistance Publique-Hôpitaux de Paris, Hôpital Lariboisière, Fédération de Rhumatologie, 75010, Paris, France.
BMC Musculoskelet Disord. 2011 Apr 12;12:72. doi: 10.1186/1471-2474-12-72.
To compare the prescription modalities of general practitioners (GPs) and rheumatologists (RHs) for symptomatic knee osteoarthritis (OA) and to determine correlates with prescription of low-dose NSAIDs.
This observational, prospective, national survey was carried out among a national representative sample of GPs (n = 808) and RHs (n = 134). Each physician completed a medical questionnaire for the 2 most recent patients fulfilling the ACR criteria for knee OA.
GPs and RHs included 1,570 and 251 patients, respectively. Mean pain level of the knee (on a VAS, 0-100 mm) was greater for GP patients than for RH patients (49.8 ± 16.3 vs. 46.2 ± 17.1 mm, respectively; p < 0.01). As compared with patients of RHs, those of GPs more frequently had another joint affected by OA: 71.2% vs. 63.7% (p < 0.0001) and more often had hypertension and diabetes mellitus (p < 0.05). As compared with RHs, GPs more frequently prescribed low-dose NSAIDs (p < 0.0001), oral NSAIDs (p < 0.05), and topical NSAIDs (p < 0.0001) but less frequently symptomatic slow-acting drugs for OA (p < 0.01). Moreover, GPs more frequently recommended rehabilitation (p < 0.01) and loss of weight (p < 0.0001). Logistic regression analysis revealed an association of low-dose NSAIDs prescription and prescription by GPs, prescription of topical NSAIDs, no prescription of oral NSAIDs or coxibs and no intra-articular injection of steroids.
This study identified speciality-related variability in some aspects of the management of knee OA. The clinical profile of patients with knee OA differed between GPs and RHs.
比较全科医生(GP)和风湿病医生(RH)治疗膝关节骨关节炎(OA)症状的处方模式,并确定与开具低剂量 NSAIDs 相关的因素。
这项观察性、前瞻性的全国性调查是在全国代表性的 GP(n=808)和 RH(n=134)样本中进行的。每位医生都为最近符合膝关节 OA ACR 标准的 2 名患者填写了一份医学问卷。
GP 和 RH 分别纳入了 1570 名和 251 名患者。GP 患者膝关节疼痛程度(VAS,0-100mm)高于 RH 患者(分别为 49.8±16.3mm 和 46.2±17.1mm;p<0.01)。与 RH 患者相比,GP 患者更常有关节 OA 累及其他关节:71.2%比 63.7%(p<0.0001),且更常患有高血压和糖尿病(p<0.05)。与 RH 相比,GP 更常开具低剂量 NSAIDs(p<0.0001)、口服 NSAIDs(p<0.05)和局部 NSAIDs(p<0.0001),但更常开具 OA 症状缓解慢作用药物(p<0.01)。此外,GP 更常建议康复(p<0.01)和减轻体重(p<0.0001)。Logistic 回归分析显示,低剂量 NSAIDs 处方和 GP 处方、局部 NSAIDs 处方、无口服 NSAIDs 或 Coxibs 处方以及关节内注射类固醇无处方与低剂量 NSAIDs 处方相关。
本研究发现膝关节 OA 管理的某些方面存在专业相关的变异性。膝关节 OA 患者的临床特征在 GP 和 RH 之间存在差异。