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比较全科医生和风湿病学家治疗膝关节骨关节炎患者的处方模式。

Comparison of general practitioners and rheumatologists' prescription patterns for patients with knee osteoarthritis.

机构信息

Univ Paris Diderot, Sorbonne Paris Cité, Assistance Publique-Hôpitaux de Paris, Hôpital Lariboisière, Fédération de Rhumatologie, 75010, Paris, France.

出版信息

BMC Musculoskelet Disord. 2011 Apr 12;12:72. doi: 10.1186/1471-2474-12-72.

Abstract

BACKGROUND

To compare the prescription modalities of general practitioners (GPs) and rheumatologists (RHs) for symptomatic knee osteoarthritis (OA) and to determine correlates with prescription of low-dose NSAIDs.

METHODS

This observational, prospective, national survey was carried out among a national representative sample of GPs (n = 808) and RHs (n = 134). Each physician completed a medical questionnaire for the 2 most recent patients fulfilling the ACR criteria for knee OA.

RESULTS

GPs and RHs included 1,570 and 251 patients, respectively. Mean pain level of the knee (on a VAS, 0-100 mm) was greater for GP patients than for RH patients (49.8 ± 16.3 vs. 46.2 ± 17.1 mm, respectively; p < 0.01). As compared with patients of RHs, those of GPs more frequently had another joint affected by OA: 71.2% vs. 63.7% (p < 0.0001) and more often had hypertension and diabetes mellitus (p < 0.05). As compared with RHs, GPs more frequently prescribed low-dose NSAIDs (p < 0.0001), oral NSAIDs (p < 0.05), and topical NSAIDs (p < 0.0001) but less frequently symptomatic slow-acting drugs for OA (p < 0.01). Moreover, GPs more frequently recommended rehabilitation (p < 0.01) and loss of weight (p < 0.0001). Logistic regression analysis revealed an association of low-dose NSAIDs prescription and prescription by GPs, prescription of topical NSAIDs, no prescription of oral NSAIDs or coxibs and no intra-articular injection of steroids.

CONCLUSIONS

This study identified speciality-related variability in some aspects of the management of knee OA. The clinical profile of patients with knee OA differed between GPs and RHs.

摘要

背景

比较全科医生(GP)和风湿病医生(RH)治疗膝关节骨关节炎(OA)症状的处方模式,并确定与开具低剂量 NSAIDs 相关的因素。

方法

这项观察性、前瞻性的全国性调查是在全国代表性的 GP(n=808)和 RH(n=134)样本中进行的。每位医生都为最近符合膝关节 OA ACR 标准的 2 名患者填写了一份医学问卷。

结果

GP 和 RH 分别纳入了 1570 名和 251 名患者。GP 患者膝关节疼痛程度(VAS,0-100mm)高于 RH 患者(分别为 49.8±16.3mm 和 46.2±17.1mm;p<0.01)。与 RH 患者相比,GP 患者更常有关节 OA 累及其他关节:71.2%比 63.7%(p<0.0001),且更常患有高血压和糖尿病(p<0.05)。与 RH 相比,GP 更常开具低剂量 NSAIDs(p<0.0001)、口服 NSAIDs(p<0.05)和局部 NSAIDs(p<0.0001),但更常开具 OA 症状缓解慢作用药物(p<0.01)。此外,GP 更常建议康复(p<0.01)和减轻体重(p<0.0001)。Logistic 回归分析显示,低剂量 NSAIDs 处方和 GP 处方、局部 NSAIDs 处方、无口服 NSAIDs 或 Coxibs 处方以及关节内注射类固醇无处方与低剂量 NSAIDs 处方相关。

结论

本研究发现膝关节 OA 管理的某些方面存在专业相关的变异性。膝关节 OA 患者的临床特征在 GP 和 RH 之间存在差异。

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