Department of Applied Physical Therapy, Shinshu University School of Health Sciences, Asahi 3-1-1, Matsumoto, Nagano, 390-8621, Japan.
Chem Soc Rev. 2011 Jul;40(7):3824-34. doi: 10.1039/c0cs00120a. Epub 2011 Apr 13.
Carbon fibers are state-of-the-art materials with properties that include being light weight, high strength, and chemically stable, and are applied in various fields including aeronautical science and space science. Investigation of applications of carbon fibers to biomaterials was started 30 or more years ago, and various products have been developed. Because the latest technological progress has realized nano-level control of carbon fibers, applications to biomaterials have also progressed to the age of nano-size. Carbon fibers with diameters in the nano-scale (carbon nanofibers) dramatically improve the functions of conventional biomaterials and make the development of new composite materials possible. Carbon nanofibers also open possibilities for new applications in regenerative medicine and cancer treatment. The first three-dimensional constructions with carbon nanofibers have been realized, and it has been found that the materials could be used as excellent scaffolding for bone tissue regeneration. In this critical review, we summarize the history of carbon fiber application to the biomaterials and describe future perspectives in the new age of nano-level control of carbon fibers (122 references).
碳纤维是一种先进的材料，具有重量轻、强度高、化学稳定性好等特点，广泛应用于航空航天等各个领域。对碳纤维在生物材料中应用的研究始于 30 多年前，已经开发出了各种产品。由于最新的技术进步实现了对碳纤维的纳米级控制，碳纤维在生物材料中的应用也进入了纳米尺寸时代。直径在纳米级（碳纤维纳米纤维）的碳纤维极大地提高了传统生物材料的功能，并使新型复合材料的开发成为可能。碳纤维纳米纤维也为再生医学和癌症治疗的新应用开辟了可能性。已经实现了具有碳纤维的第一个三维结构，并且发现这些材料可用作骨组织再生的极好支架。在这篇重要的综述中，我们总结了碳纤维在生物材料中应用的历史，并描述了在碳纤维纳米级控制的新时代的未来展望（122 篇参考文献）。
